Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6998834 | 0.92 | — | — | |
| SCHEMBL6997722 | 0.90 | — | — | |
| SCHEMBL18227311 | 0.73 | TSHR (0.36) | — | |
| SCHEMBL6141036 | 0.72 | — | — | |
| SCHEMBL8848780 | 0.72 | TSHR (0.34) | MEN1ALDH1A1KMT2A | |
| SCHEMBL20130263 | 0.72 | MEN1 (0.33) | MEN1ALDH1A1KMT2A | |
| SCHEMBL3183822 | 0.71 | TSHR (0.34) | MEN1ALDH1A1KMT2A | |
| SCHEMBL21236739 | 0.70 | — | — | |
| SCHEMBL17256253 | 0.70 | TSHR (0.41) | — | |
| SCHEMBL19153446 | 0.69 | KDM4E (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160195540-A1 | Molecular Conjugate | VENTANA MED SYST INC (US) | 2016-07-07 | — | — | US | disclosed |
| US-9310373-B2 | Molecular conjugate | VENTANA MEDICAL SYSTEMS, INC. (US) | 2016-04-12 | — | — | US | disclosed |
| US-20140205995-A1 | MOLECULAR CONJUGATE | VENTANA MEDICAL SYSTEMS, INC. (US) | 2014-07-24 | — | — | US | disclosed |
| US-8183355-B2 | Method for the synthesis of oligonucleotide derivatives | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2012-05-22 | — | — | US | disclosed |
| US-20110245478-A1 | Method for the Synthesis of Oligonucleotide Derivatives | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) | 2011-10-06 | — | — | US | disclosed |
| US-7951926-B2 | Method for the synthesis of oligonucleotide derivatives | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2011-05-31 | — | — | US | disclosed |
| US-20090124571-A1 | METHOD FOR THE SYNTHESIS OF OLIGONUCLEOTIDE DERIVATIVES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2009-05-14 | — | — | US | disclosed |
| WO-2007125429-A2 | METHOD FOR THE SYNTHESIS OF TRIAZOLE- CONTAINING OLIGONUCLEOTIDE DERIVATIVES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2007-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160195540-A1 | Molecular Conjugate | CA12, FCGR2A, CA14 | MEN1 3359/4885ALDH1A1 41/4885KMT2A 181/4885 |
| US-20090124571-A1 | METHOD FOR THE SYNTHESIS OF OLIGONUCLEOTIDE DERIVATIVES | MSN, RNGTT, DCLRE1B | MEN1 2776/4885ALDH1A1 1935/4885KMT2A 2564/4885 |
| US-20110245478-A1 | Method for the Synthesis of Oligonucleotide Derivatives | MSN, RNGTT, DCLRE1B | MEN1 2776/4885ALDH1A1 1935/4885KMT2A 2564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.