Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 16/20 | 0.74 |
| ▸ | KDR | P35968 | 15/20 | 0.74 |
| ▸ | FGFR1 | P11362 | 13/20 | 0.74 |
| ▸ | SRC | P12931 | 3/20 | 0.62 |
| ▸ | FLT4 | P35916 | 7/20 | 0.59 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 7/20 | 0.58 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.51 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.51 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6434784 | 0.99 | FLT1 (0.72) | FLT1KDRFGFR1SRCFLT4 | |
| Hydrochloric Acid SCHEMBL6434964 | 0.88 | FLT1 (0.82) | FLT1KDRFGFR1SRCFLT4 | |
| SCHEMBL18979021 | 0.86 | FLT1 (0.84) | FLT1KDRFGFR1SRCFLT4 | |
| SCHEMBL6430998 | 0.86 | FLT1 (0.75) | FLT1KDRFGFR1SRCFLT4 | |
| Hydrochloric Acid SCHEMBL1467888 | 0.85 | FLT1 (0.82) | FLT1KDRFGFR1SRCFLT4 | |
| SCHEMBL28468523 | 0.85 | EGFR (0.59) | FLT1KDRFGFR1SRCEPHB2 | |
| Hydrochloric Acid SCHEMBL6431427 | 0.85 | FLT1 (0.74) | FLT1KDRFGFR1SRCFLT4 | |
| SCHEMBL6431198 | 0.85 | FLT1 (1.00) | FLT1KDRFGFR1SRCFLT4 | |
| Hydrochloric Acid SCHEMBL6431524 | 0.84 | FLT1 (0.98) | FLT1KDRFGFR1SRCFLT4 | |
| SCHEMBL6434256 | 0.84 | FLT1 (0.83) | FLT1KDRFGFR1SRCFLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003526686-A | — | — | 2003-09-09 | — | — | JP | claimed |
| EP-1263503-A2 | USE OF CYANOQUINOLINES FOR TREATING OR INHIBITING COLONIC POLYPS | AMERICAN CYANAMID COMPANY (US) | 2002-12-11 | — | — | EP | claimed |
| WO-2001068186-A2 | USE OF CYANOQUINOLINES FOR TREATING OR INHIBITING COLONIC POLYPS | AMERICAN CYANAMID COMPANY (US) | 2001-09-20 | — | — | WO | claimed |
| EP-0973746-A1 | SUBSTITUTED 3-CYANO QUINOLINES | American Cyanamid Company (US) | 2000-01-26 | — | — | EP | claimed |
| WO-1998043960-A1 | SUBSTITUTED 3-CYANO QUINOLINES | AMERICAN CYANAMID COMPANY (US) | 1998-10-08 | — | — | WO | claimed |