Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 18/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14491417 | 0.78 | LMNA (0.47) | TACR1MEN1KMT2A | |
| SCHEMBL13067039 | 0.71 | KCNA3 (0.44) | MEN1KMT2A | |
| SCHEMBL5378383 | 0.70 | TACR1 (1.00) | TACR1SLC6A4 | |
| SCHEMBL5382978 | 0.70 | TACR1 (1.00) | TACR1SLC6A4 | |
| SCHEMBL5382653 | 0.70 | TACR1 (1.00) | TACR1SLC6A4 | |
| SCHEMBL5382646 | 0.70 | TACR1 (1.00) | TACR1SLC6A4 | |
| SCHEMBL8824360 | 0.69 | TACR1 (0.63) | TACR1SLC6A4 | |
| SCHEMBL5766892 | 0.69 | TACR1 (0.59) | TACR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9391402 | 0.68 | TACR1 (0.61) | TACR1SLC6A4 | |
| SCHEMBL6486421 | 0.68 | TACR1 (0.66) | TACR1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286967-A1 | CYCLOHEXANE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | MERCK SHARP & DOHME LTD. (GB) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001087838-A1 | CYCLOHEXANE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | MERCK SHARP & DOHME LIMITED (GB) | 2001-11-22 | — | — | WO | disclosed |