Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 9/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7582468 | 0.86 | EGFR (0.51) | EGFRERBB2HPGDHTTMAPT | |
| SCHEMBL7582476 | 0.86 | EGFR (0.51) | EGFRERBB2HPGDHTTMAPT | |
| SCHEMBL7580691 | 0.84 | EGFR (0.53) | EGFRERBB2HPGDHTTMAPT | |
| SCHEMBL7580700 | 0.84 | EGFR (0.53) | EGFRERBB2HPGDHTTMAPT | |
| SCHEMBL6999534 | 0.84 | EGFR (0.51) | EGFRERBB2HPGDHTTMAPT | |
| SCHEMBL6999540 | 0.84 | EGFR (0.51) | EGFRERBB2HPGDHTTMAPT | |
| SCHEMBL7585796 | 0.83 | EGFR (0.52) | EGFRERBB2HPGDHTTMAPT | |
| SCHEMBL7585793 | 0.83 | EGFR (0.52) | EGFRERBB2HPGDHTTMAPT | |
| SCHEMBL7584883 | 0.82 | EGFR (0.53) | EGFRERBB2HPGDHTTMAPT | |
| SCHEMBL7584865 | 0.82 | EGFR (0.53) | EGFRERBB2HPGDHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888351-B1 | PYRIMIDO 5,4-D]PYRIMIDINES, MEDICAMENTS CONTAINING THESE COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PRODUCTION | THOMAE GMBH DR K (DE) | 2003-10-15 | — | — | EP | disclosed |