Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6998367 | 0.79 | SLC6A3 (1.00) | SLC6A3ALDH1A1TSHRKMT2AMAPT | |
| SCHEMBL11543984 | 0.72 | SLC6A3 (0.56) | SLC6A3ALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL6041278 | 0.72 | KMT2A (0.59) | SLC6A3ALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL10655668 | 0.71 | SLC6A3 (0.55) | SLC6A3ALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL10655671 | 0.71 | SLC6A3 (0.55) | SLC6A3ALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL10852753 | 0.71 | SLC6A3 (0.55) | SLC6A3ALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL7001985 | 0.70 | KMT2A (0.79) | SLC6A3ALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL11544023 | 0.70 | SLC6A3 (0.54) | SLC6A3ALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL6043390 | 0.69 | KMT2A (0.55) | SLC6A3ALDH1A1TSHRKMT2AMAPT | |
| SCHEMBL23962430 | 0.69 | SLC6A3 (0.52) | SLC6A3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242080-A4 | DOPAMINE TRANSPORTER INHIBITORS AND THEIR USE | UNIV GEORGETOWN (US) | 2003-01-22 | — | — | EP | claimed |
| EP-1242080-A1 | DOPAMINE TRANSPORTER INHIBITORS AND THEIR USE | GEORGETOWN UNIVERSITY (US) | 2002-09-25 | — | — | EP | claimed |
| WO-2001022964-A1 | DOPAMINE TRANSPORTER INHIBITORS AND THEIR USE | GEORGETOWN UNIVERSITY (US) | 2001-04-05 | — | — | WO | claimed |
| EP-1242080-A4 | DOPAMINE TRANSPORTER INHIBITORS AND THEIR USE | UNIV GEORGETOWN (US) | 2003-01-22 | — | — | EP | disclosed |
| EP-1242080-A1 | DOPAMINE TRANSPORTER INHIBITORS AND THEIR USE | GEORGETOWN UNIVERSITY (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001022964-A1 | DOPAMINE TRANSPORTER INHIBITORS AND THEIR USE | GEORGETOWN UNIVERSITY (US) | 2001-04-05 | — | — | WO | disclosed |