Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.42 |
| ▸ | BRD4 | O60885 | 3/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phensuximide SCHEMBL35333 | 0.77 | KMT2A (1.00) | KMT2ATSHRMEN1SMN1; SMN2L3MBTL1 | |
| Phensuximide SCHEMBL35334 | 0.77 | KMT2A (1.00) | KMT2ATSHRMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL2924606 | 0.77 | KMT2A (0.62) | KMT2ATSHRMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL16350192 | 0.77 | TSHR (0.62) | KMT2ATSHRMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL11050716 | 0.76 | KMT2A (0.61) | KMT2ATSHRMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL3602720 | 0.75 | ALDH1A1 (0.59) | KMT2ATSHRMEN1SMN1; SMN2HPGD | |
| SCHEMBL20079364 | 0.74 | CYP19A1 (0.73) | KMT2ATSHRMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL16017647 | 0.73 | KMT2A (0.62) | KMT2ATSHRMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL11059283 | 0.73 | KMT2A (0.57) | KMT2ATSHRMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL13495371 | 0.73 | KMT2A (0.62) | KMT2ATSHRMEN1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6642256-B2 | Brain disorders, psychological disorders, antiischemic agents, central nervous system disorders | WARNER-LAMBERT COMPANY LLC | 2003-11-04 | — | — | US | disclosed |
| EP-1345935-A2 | PIPERIDINE DERIVATIVES AS SUBTYPE SELECTIVE N-METHYL-D-ASPARTATE ANTAGONISTS | Warner-Lambert Company LLC (US) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002050070-A2 | PIPERIDINE DERIVATIVES AS SUBTYPE SELECTIVE N-METHYL-D-ASPARTATE ANTAGONISTS | WARNER-LAMBERT COMPANY LLC (US) | 2002-06-27 | — | — | WO | disclosed |