Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 6/20 | 0.42 |
| ▸ | FNTB | P49356 | 6/20 | 0.42 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13681920 | 0.85 | TERT (0.40) | FNTAFNTBMAPT | |
| SCHEMBL6991517 | 0.85 | MAP3K14 (0.44) | FNTAFNTBMAP3K14P2RX7 | |
| SCHEMBL1978262 | 0.78 | FNTA (0.60) | FNTAFNTB | |
| SCHEMBL7000351 | 0.77 | FNTA (0.71) | FNTAFNTB | |
| SCHEMBL6991223 | 0.74 | FNTA (0.52) | FNTAFNTB | |
| SCHEMBL9261841 | 0.72 | FNTA (0.54) | FNTAFNTB | |
| SCHEMBL11277012 | 0.72 | HTR2B (0.40) | MAP3K14MAPTRXFP1 | |
| SCHEMBL9563101 | 0.71 | FNTA (0.60) | FNTAFNTB | |
| SCHEMBL6998860 | 0.69 | FNTA (0.49) | FNTAFNTB | |
| SCHEMBL38663475 | 0.68 | FNTA (0.47) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7585864-B2 | Farnesyl protein transferase inhibitors and their use to treat cancer | SCHERING CORPORATION (US) | 2009-09-08 | — | — | US | disclosed |
| US-7585864-B2 | Farnesyl protein transferase inhibitors and their use to treat cancer | SCHERING CORPORATION (US) | 2009-09-08 | — | — | US | disclosed |
| EP-1021448-B1 | TRICYCLIC COMPOUNDS HAVING ACTIVITY AS Ras-FPT INHIBITORS | SCHERING CORP (US) | 2003-05-02 | — | — | EP | disclosed |
| US-6130229-A | Tricyclic compounds having activity as RAS-FPT inhibitors | SCHERING CORPORATION (US) | 2000-10-10 | — | — | US | disclosed |
| EP-1021448-A1 | TRICYCLIC COMPOUNDS HAVING ACTIVITY AS Ras-FPT INHIBITORS | SCHERING CORPORATION (US) | 2000-07-26 | — | — | EP | disclosed |
| WO-1998015556-A1 | TRICYCLIC COMPOUNDS HAVING ACTIVITY AS Ras-FPT INHIBITORS | SCHERING CORPORATION (US) | 1998-04-16 | — | — | WO | disclosed |
| EP-0535152-B1 | Bis-benzo or benzopyrido cyclo hepta piperidene, piperidylene and piperazine compounds as PAF antagonists and compositions thereof. | SCHERING CORP (US) | 1995-08-09 | — | — | EP | disclosed |
| US-5430032-A | Treating asthma, allergy, inflammation | SCHERING CORPORATION (US) | 1995-07-04 | — | — | US | disclosed |
| US-5422351-A | Antiallergens; antiinflammatory agents | SCHERING CORPORATION (US) | 1995-06-06 | — | — | US | disclosed |
| EP-0595989-A1 | BENZOPYRIDO PIPERYLIDENE COMPOUNDS, COMPOSITIONS, METHODS OF MANUFACTURE AND METHODS OF USE | SCHERING CORPORATION (US) | 1994-05-11 | — | — | EP | disclosed |
| EP-0535152-A1 | BIS-BENZO OR BENZOPYRIDO CYCLO HEPTA PIPERIDENE, PIPERIDYLIDENE AND PIPERAZINE COMPOUNDS AND COMPOSITIONS. | SCHERING CORP (US) | 1993-04-07 | — | — | EP | disclosed |
| WO-1993002081-A1 | NOVEL BENZOPYRIDO PIPERYLIDENE COMPOUNDS, COMPOSITIONS, METHODS OF MANUFACTURE AND METHODS OF USE | SCHERING CORPORATION (US) | 1993-02-04 | — | — | WO | disclosed |
| EP-0524784-A1 | Benzopyrido piperidylidene compounds as PAF antagonists | SCHERING CORPORATION (US) | 1993-01-27 | — | — | EP | disclosed |
| WO-1992000293-A1 | BIS-BENZO OR BENZOPYRIDO CYCLO HEPTA PIPERIDENE, PIPERIDYLIDENE AND PIPERAZINE COMPOUNDS AND COMPOSITIONS | SCHERING CORPORATION (US) | 1992-01-09 | — | — | WO | disclosed |