Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | BID | P55957 | 3/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.51 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.51 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.51 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | EP300 | Q09472 | 1/20 | 0.51 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.51 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.51 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.51 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31545728 | 1.00 | HTT (0.52) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL876099 | 0.98 | BID (0.54) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL22501541 | 0.98 | BID (0.54) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL29108 | 0.98 | BID (0.54) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL9784636 | 0.98 | BID (0.54) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL17938799 | 0.98 | BID (0.54) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL16528762 | 0.98 | BID (0.54) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL70428 | 0.98 | BID (0.54) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL2370347 | 0.98 | BID (0.54) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL31545793 | 0.98 | BID (0.54) | HTTNPC1HPGDMAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 589 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12053537-B2 | Reduction of stinging sensation on skin | SYMRISE AG (DE) | 2024-08-06 | — | — | US | claimed |
| CN-108472220-B | Reducing the perception of skin stinging | 西姆莱斯股份公司 | 2022-06-17 | — | — | CN | claimed |
| EP-3373895-B1 | REDUCTION OF STINGING SENSATION ON SKIN | SYMRISE AG (DE) | 2020-08-19 | — | — | EP | claimed |
| CN-104414869-B | A kind of skin and/or hair whitening mixture | 西姆莱斯股份公司 | 2019-09-03 | — | — | CN | claimed |
| CN-109988213-A | A kind of compound and its preparation method and application for peptide synthesis in liquid phase carrier | 深圳翰宇药业股份有限公司 | 2019-07-09 | — | — | CN | claimed |
| EP-3373895-A1 | REDUCTION OF STINGING SENSATION ON SKIN | Symrise AG (DE) | 2018-09-19 | — | — | EP | claimed |
| EP-2842607-B1 | A skin and/or hair whitening mixture | SYMRISE AG (DE) | 2018-05-30 | — | — | EP | claimed |
| WO-2017080625-A1 | REDUCTION OF STINGING SENSATION ON SKIN | SYMRISE AG (DE) | 2017-05-18 | — | — | WO | claimed |
| CN-104414869-A | SKIN AND/OR HAIR WHITENING MIXTURE | SYMRISE AG | 2015-03-18 | — | — | CN | claimed |
| US-20150064122-A1 | SKIN AND/OR HAIR WHITENING MIXTURE | SYMRISE AG (DE) | 2015-03-05 | — | — | US | claimed |
| CN-1736974-A | Special alembic for disposing vinyl acetate waste slag of alembic bottom and waste slag processing method | WAN XIAOWEN (CN) | 2006-02-22 | — | — | CN | claimed |
| WO-2005107456-A2 | ANTIMICROBIAL SILICON OXIDE FLAKES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-11-17 | — | — | WO | claimed |
| EP-1537201-A1 | HARD SURFACE TREATING COMPOSITIONS | Reckitt Benckiser Inc. (US) | 2005-06-08 | — | — | EP | claimed |
| WO-2004024861-A1 | HARD SURFACE TREATING COMPOSITIONS | RECKITT BENCKISER INC (US) | 2004-03-25 | — | — | WO | claimed |
| WO-2003082948-A1 | A METHOD OF ALIGNING POLYMER CHAINS | TEKNILLINEN KORKEAKOULU (FI) | 2003-10-09 | — | — | WO | claimed |
| EP-0331422-A2 | Method of preparing 2-acylresorcinols | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1989-09-06 | — | — | EP | claimed |
| EP-0021716-B1 | CONDENSATION PRODUCT AND LITHOGRAPHIC PRINTING PLATES CONTAINING SAID PRODUCT | KONICA CORPORATION (JP) | 1984-02-15 | — | — | EP | claimed |
| EP-0001617-B1 | DIAZOTYPE MATERIAL | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-22 | — | — | EP | claimed |
| US-4207110-A | 2,5-DIALKOXY-4-MORPHOLINO-BENZENE DIAZONIUM SALT AND COUPLER COMBINATION TO GIVE BLACK IMAGE | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-06-10 | — | — | US | claimed |
| EP-0001617-A1 | Diazotype material | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-02 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12053537-B2 | Reduction of stinging sensation on skin | STING1, TYR, CUTA | HTT 4421/4885NPC1 1983/4885HPGD 1478/4885 |
| US-20150064122-A1 | SKIN AND/OR HAIR WHITENING MIXTURE | TYR, AHR, CYP1B1 | HTT 1679/4885NPC1 3089/4885HPGD 1470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.