Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6997757 | 0.83 | F10 (0.66) | F10F2 | |
| SCHEMBL7002616 | 0.83 | KCNH2 (0.56) | F10 | |
| SCHEMBL6696436 | 0.82 | F10 (0.72) | F10F2 | |
| SCHEMBL6696448 | 0.81 | F10 (0.64) | F10F2 | |
| SCHEMBL6697949 | 0.80 | F10 (0.64) | F10 | |
| SCHEMBL6697983 | 0.80 | F10 (0.69) | F10 | |
| SCHEMBL6697986 | 0.79 | F10 (0.63) | F10 | |
| SCHEMBL1651371 | 0.78 | F10 (0.82) | F10 | |
| SCHEMBL4385622 | 0.78 | F10 (0.82) | F10 | |
| SCHEMBL1652020 | 0.78 | F10 (0.82) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322643-A1 | PIPERAZIN-2-ONE AMIDES AS INHIBITORS OF FACTOR XA | Millennium Pharmaceuticals, Inc. (US) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002026734-A1 | PIPERAZIN-2-ONE AMIDES AS INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2002-04-04 | — | — | WO | disclosed |