Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CCR1 | P32246 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CCR3 | P51677 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4313992 | 0.99 | MEN1 (0.49) | MEN1KMT2ACCR1GAASMN1; SMN2 | |
| SCHEMBL1672736 | 0.99 | MEN1 (0.49) | MEN1KMT2ACCR1GAASMN1; SMN2 | |
| SCHEMBL1672735 | 0.99 | MEN1 (0.49) | MEN1KMT2ACCR1GAASMN1; SMN2 | |
| Lithium Ion SCHEMBL700121 | 0.90 | MEN1 (0.47) | MEN1KMT2ACCR1GAASMN1; SMN2 | |
| Lithium Ion SCHEMBL701964 | 0.90 | MEN1 (0.47) | MEN1KMT2ACCR1GAASMN1; SMN2 | |
| SCHEMBL702595 | 0.90 | MEN1 (0.47) | MEN1KMT2ACCR1CCR3 | |
| SCHEMBL702594 | 0.90 | MEN1 (0.47) | MEN1KMT2ACCR1CCR3 | |
| SCHEMBL703073 | 0.90 | MEN1 (0.47) | MEN1KMT2ACCR1CCR3 | |
| SCHEMBL1672707 | 0.83 | MEN1 (0.47) | MEN1KMT2AGAASMN1; SMN2CHRM2 | |
| SCHEMBL703142 | 0.83 | CHRM2 (0.41) | GAACHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124600-B2 | 5-HT3 receptor modulators, methods of making, and use thereof | ALBANY MOLECULAR RESEARCH, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| EP-2310019-A2 | 5-HT3 RECEPTOR MODULATORS, METHODS OF MAKING, AND USE THEREOF | Albany Molecular Research, Inc. (US) | 2011-04-20 | — | — | EP | disclosed |