Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | GFER | P55789 | 1/20 | 0.64 |
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
| ▸ | PPARA | Q07869 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | METAP2 | P50579 | 2/20 | 0.54 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.54 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | PLK1 | P53350 | 6/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4839372 | 0.89 | MEN1 (0.68) | KDM4EHSD17B10KMT2AMEN1GFER | |
| SCHEMBL14822784 | 0.87 | KMT2A (0.53) | KDM4EHSD17B10KMT2AMEN1GFER | |
| SCHEMBL6891543 | 0.85 | KMT2A (0.55) | KDM4EHSD17B10KMT2AMEN1GFER | |
| SCHEMBL14400504 | 0.84 | HPGD (0.68) | KMT2AMEN1GFERPPARGPPARA | |
| SCHEMBL7850074 | 0.84 | PTPN1 (0.65) | KMT2AMEN1GFERPPARGPPARA | |
| SCHEMBL14426494 | 0.83 | MEN1 (0.66) | KMT2AMEN1GFERALDH1A1MAPT | |
| SCHEMBL31451940 | 0.83 | KDM4E (0.69) | KDM4EHSD17B10KMT2AMEN1GFER | |
| SCHEMBL8533041 | 0.83 | KDM4E (0.69) | KDM4EHSD17B10KMT2AMEN1GFER | |
| SCHEMBL8340439 | 0.82 | MEN1 (0.60) | KMT2AMEN1GFERPPARGPPARA | |
| SCHEMBL11803827 | 0.81 | KDM4E (0.67) | KDM4EHSD17B10KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101693666-A | Stilbene derivative | UNIV SUZHOU | 2010-04-14 | — | — | CN | disclosed |
| US-20080171891-A1 | Process for preparing carbamic ester derivatives | HOLZER BETTINA | 2008-07-17 | — | — | US | disclosed |
| US-7396952-B2 | Process for preparing carbamic ester derivatives | LANXESS DEUTSCHLAND GMBH (DE) | 2008-07-08 | — | — | US | disclosed |
| US-20070232825-A1 | Process for preparing carbamic ester derivatives | LANXESS DEUTSCHLAND GMBH (DE) | 2007-10-04 | — | — | US | disclosed |
| EP-0980374-B1 | PHOSPHODIESTERASE 4-INHIBITING DIAZEPINOINDOLONES | PFIZER HOLDING FRANCE (FR) | 2003-02-12 | — | — | EP | disclosed |
| US-6239130-B1 | ASTHMA, ATOPIC DERMATITIS, RHEUMATOID ARTHRITIS, INFLAMMATORY BOWEL DISORDERS, PULMONARY HYPERTENSION, LIVER INJURY, BONE LOSS, SEPTIC SHOCK, OR MULTIPLE SCLEROSIS, | WARNER-LAMBERT COMPANY | 2001-05-29 | — | — | US | disclosed |
| EP-0980374-A1 | PHOSPHODIESTERASE 4-INHIBITING DIAZEPINOINDOLONES | PARKE-DAVIS (FR) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998049169-A1 | PHOSPHODIESTERASE 4-INHIBITING DIAZEPINOINDOLONES | PARKE-DAVIS (FR) | 1998-11-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171891-A1 | Process for preparing carbamic ester derivatives | CPS1, CA7, CA4 | KDM4E 128/4885HSD17B10 718/4885KMT2A 1072/4885 |
| US-20070232825-A1 | Process for preparing carbamic ester derivatives | CPS1, CA7, CA4 | KDM4E 128/4885HSD17B10 718/4885KMT2A 1072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.