SCHEMBL70017

SCHEMBL70017

O=C(O)c1cc2ccccc2nc1C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.61
SMN1; SMN2 Q16637 3/20 0.61
MAPT P10636 2/20 0.61
KDM4E B2RXH2 3/20 0.60
MEN1 O00255 2/20 0.60
KMT2A Q03164 2/20 0.60
IKBKB O14920 1/20 0.51
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
MGAM O43451 2/20 0.49
IDO1 P14902 1/20 0.48
HPGD P15428 2/20 0.46
GLA P06280 1/20 0.46
ACHE P22303 1/20 0.46
LMNA P02545 1/20 0.46
PDE10A Q9Y233 1/20 0.46
PTPN1 P18031 1/20 0.46
TSHR P16473 1/20 0.45
DHODH Q02127 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30034075 1.00 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2MAPTKDM4EMEN1
Water SCHEMBL10410161 0.98 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2MAPTKDM4EMEN1
SCHEMBL28389068 0.98 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2MAPTKDM4EMEN1
Water SCHEMBL10472756 0.98 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2MAPTKDM4EMEN1
Hydrochloric Acid SCHEMBL9622111 0.98 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2MAPTKDM4EMEN1
Formic Acid SCHEMBL27968869 0.93 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2MAPTKDM4EMEN1
Butane SCHEMBL9352014 0.92 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2MAPTKDM4EMEN1
Hydrochloric Acid SCHEMBL9681933 0.87 ALDH1A1 (0.49) ALDH1A1SMN1; SMN2MAPTKDM4EMEN1
SCHEMBL9632211 0.87 ALDH1A1 (0.51) ALDH1A1SMN1; SMN2MAPTKDM4EMEN1
SCHEMBL9330051 0.87 IKBKB (0.60) ALDH1A1SMN1; SMN2MAPTKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 461 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115873236-B Method and system for preparing high-temperature-resistant nylon by continuous polymerization 浙江新力新材料股份有限公司 2024-08-27 CN claimed
CN-118080011-A Catalyst for preparing methanol by hydrogenation of carbon dioxide, preparation method and application thereof 国家能源集团新能源技术研究院有限公司 2024-05-28 CN claimed
CN-118085557-A Automotive interior injection molding material and preparation method thereof 扬州维辰汽车电子有限公司 2024-05-28 CN claimed
CN-117866621-A Method for enhancing luminescence performance of delayed fluorescence anti-counterfeiting material 昆明理工大学 2024-04-12 CN claimed
CN-117343508-B Flame-retardant base film for composite current collector and preparation method thereof 扬州博恒新能源材料科技有限公司 2024-02-20 CN claimed
CN-117534416-A Green high-performance concrete 江苏立浩建材科技有限公司 2024-02-09 CN claimed
CN-117510178-A Polymer bentonite composite impermeable material and preparation method thereof 济源职业技术学院 2024-02-06 CN claimed
CN-117429153-A Electrolyte corrosion-resistant aluminum-plastic film and preparation method thereof 信阳华谷新材料科技有限公司 2024-01-23 CN claimed
CN-117343508-A Flame-retardant base film for composite current collector and preparation method thereof 扬州博恒新能源材料科技有限公司 2024-01-05 CN claimed
CN-117304589-A Wear-resistant and anti-skid sole material and preparation method thereof 朱添奇 2023-12-29 CN claimed
EP-0126893-B1 A METHOD FOR OXIDIZING ALKYL GROUPS TO CARBOXYLIC ACIDS UNDER BASIC CONDITIONS AMERICAN CYANAMID COMPANY (US) 1989-06-21 EP claimed
US-4766218-A CYCLIZATION OF DICHLOROSUCCINATE WITH AMINE AMERICAN CYANAMID COMPANY (US) 1988-08-23 US claimed
US-4757146-A Method for the preparation of quinoline-2,3-dicarboxylic acid AMERICAN CYANAMID COMPANY (US) 1988-07-12 US claimed
US-4750978-A Method for oxidizing groups to carboxylic acids under basic conditions AMERICAN CYANAMID COMPANY (US) 1988-06-14 US claimed
EP-0262305-A1 Method for the preparation of anilinofumarate and quinoline-2,3-dicarboxylic acid AMERICAN CYANAMID COMPANY (US) 1988-04-06 EP claimed
EP-0257433-A2 Method for the preparation of quinoline-2,3-dicarboxylic acid AMERICAN CYANAMID COMPANY (US) 1988-03-02 EP claimed
US-4623726-A Method for oxidizing alkyl groups on pyridine, quinoline and benzene ring compounds to carboxylic acids under basic conditions AMERICAN CYANAMID COMPANY (US) 1986-11-18 US claimed
EP-0126893-A1 A method for oxidizing alkyl groups to carboxylic acids under basic conditions AMERICAN CYANAMID COMPANY (US) 1984-12-05 EP claimed
US-4459409-A METHYL-QUINOLINECARBOXYLIC ACID, OXIDATION, NICKEL PEROXIDE AMERICAN CYANAMID COMPANY (US) 1984-07-10 US claimed
US-4439607-A FROM THE DIACID AND PHOSGENE; DIMETHYLFORMAMIDE CATALYST AMERICAN CYANAMID COMPANY (US) 1984-03-27 US claimed