Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | PPIA | P62937 | 1/20 | 0.56 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.55 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.49 |
| ▸ | PTPRC | P08575 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | F2R | P25116 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27531979 | 0.84 | LMNA (0.66) | LMNAGAAPPIAKCNK3KCNK9 | |
| SCHEMBL961793 | 0.84 | LMNA (0.66) | LMNAGAAPPIAKCNK3KCNK9 | |
| SCHEMBL9830646 | 0.82 | GAA (0.75) | LMNAGAAPPIAKCNK3KCNK9 | |
| SCHEMBL3964208 | 0.81 | LMNA (0.72) | LMNAGAAPPIAKCNK3KCNK9 | |
| SCHEMBL3418660 | 0.81 | LMNA (0.62) | LMNAGAAPPIAKCNK3KCNK9 | |
| SCHEMBL15200658 | 0.81 | LMNA (0.62) | LMNAGAAPPIAKCNK3KCNK9 | |
| SCHEMBL5332281 | 0.80 | KCNK3 (0.75) | LMNAGAAKCNK3KCNK9PTGS1 | |
| Hydrochloric Acid SCHEMBL8393906 | 0.80 | LMNA (0.60) | LMNAGAAPPIAKCNK3KCNK9 | |
| SCHEMBL6970453 | 0.79 | LMNA (0.70) | LMNAGAAPPIAKCNK3KCNK9 | |
| SCHEMBL1267035 | 0.79 | GAA (0.70) | LMNAGAAPPIAKCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874809-B1 | CARBAMOYLOXY DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2003-08-27 | — | — | EP | claimed |
| US-6239175-B1 | Carbamoyloxy derivatives of mutiline and their use as antibacterials | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-05-29 | — | — | US | claimed |
| EP-0874809-B1 | CARBAMOYLOXY DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2003-08-27 | — | — | EP | disclosed |
| US-6239175-B1 | Carbamoyloxy derivatives of mutiline and their use as antibacterials | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-05-29 | — | — | US | disclosed |
| US-6020368-A | MICROBIOCIDES | HINKS JEREMY DAVID (US) | 2000-02-01 | — | — | US | disclosed |