Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5515282 | 0.92 | LMNA (0.42) | LMNACASP3SENP8SENP7SENP6 | |
| SCHEMBL8133514 | 0.82 | HTT (0.44) | LMNACASP3SENP8SENP7SENP6 | |
| SCHEMBL8133519 | 0.78 | HTT (0.41) | LMNACASP3SENP8SENP7SENP6 | |
| SCHEMBL5512894 | 0.75 | HTT (0.42) | LMNACASP3SENP8SENP7SENP6 | |
| SCHEMBL7665569 | 0.74 | LMNA (0.42) | LMNACASP3SENP8SENP7SENP6 | |
| SCHEMBL6093550 | 0.72 | HTT (0.40) | LMNACASP3SENP8SENP7SENP6 | |
| SCHEMBL8119465 | 0.71 | LMNA (0.45) | LMNACASP3SENP8SENP7SENP6 | |
| SCHEMBL6994502 | 0.69 | LMNA (0.47) | LMNACASP3SENP8SENP7SENP6 | |
| SCHEMBL5517663 | 0.69 | LMNA (0.46) | LMNACASP3SENP8SENP7SENP6 | |
| SCHEMBL7001535 | 0.68 | LMNA (0.42) | LMNACASP3SENP8SENP7SENP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1026167-B1 | TRICYCLIC TRIAZOLOBENZAZEPINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND ANTIALLERGIC AGENTS | MEIJI SEIKA KAISHA (JP) | 2003-03-05 | — | — | EP | disclosed |