Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.49 |
| ▸ | TSHR | P16473 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6997073 | 0.87 | FSCN1 (0.54) | HTTSMN1; SMN2MMP13ALDH1A1MAPT | |
| SCHEMBL7003827 | 0.86 | SMN1; SMN2 (0.49) | HPGDLMNASMN1; SMN2POLB | |
| SCHEMBL7003576 | 0.85 | LMNA (0.48) | HPGDTSHRLMNAHTTSMN1; SMN2 | |
| SCHEMBL7081478 | 0.80 | TP53 (0.52) | TSHRLMNACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7077434 | 0.80 | KDM4E (0.45) | HPGDMMP13ALDH1A1TP53 | |
| SCHEMBL7083767 | 0.79 | MEN1 (0.43) | HPGDTSHRLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7000183 | 0.79 | SMN1; SMN2 (0.51) | HPGDLMNAHTTSMN1; SMN2MMP13 | |
| SCHEMBL7077867 | 0.78 | TSHR (0.47) | HPGDTSHRLMNAHTTSMN1; SMN2 | |
| SCHEMBL6997875 | 0.78 | CHRM1 (0.52) | HPGDTSHRLMNAHTTALDH1A1 | |
| SCHEMBL7004068 | 0.78 | SMN1; SMN2 (0.62) | HPGDTSHRLMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030186997-A1 | 2,5-Dihydro-pyrazolo[3,4-d]pyrimidin-4-ones with an anticonsulsive action and methods for producing the same | ELBION AG (DE) | 2003-10-02 | — | — | US | claimed |
| US-20030186997-A1 | 2,5-Dihydro-pyrazolo[3,4-d]pyrimidin-4-ones with an anticonsulsive action and methods for producing the same | ELBION AG (DE) | 2003-10-02 | — | — | US | disclosed |
| EP-1311510-A1 | 2,5-DIHYDRO-PYRAZOLO[3,4-D]PYRIMIDIN-4-ONES WITH AN ANTICONVULSIVE ACTION AND METHODS FOR PRODUCING THE SAME | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002018387-A1 | 2,5-DIHYDRO-PYRAZOLO[3,4-D]PYRIMIDIN-4-ONES WITH AN ANTICONVULSIVE ACTION AND METHODS FOR PRODUCING THE SAME | ELBION AG (DE) | 2002-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030186997-A1 | 2,5-Dihydro-pyrazolo[3,4-d]pyrimidin-4-ones with an anticonsulsive action and methods for producing the same | DDO, GRIN3A, GRIK4 | HPGD 291/4885TSHR 3213/4885LMNA 1746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.