Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 10/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.47 |
| ▸ | NAMPT | P43490 | 4/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.39 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7006420 | 0.86 | F10 (0.65) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7007614 | 0.86 | F10 (0.65) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL6422067 | 0.85 | F10 (0.53) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL6298107 | 0.85 | F10 (0.53) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7007797 | 0.85 | F10 (0.53) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL6424055 | 0.83 | F10 (0.53) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL6296860 | 0.83 | F10 (0.53) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL6297033 | 0.83 | F10 (0.53) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL6303645 | 0.82 | F10 (0.52) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL6298679 | 0.82 | F10 (0.54) | F10PRSS1F2PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268413-A2 | SUBSTITUTED BIPHENYL DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001070678-A2 | SUBSTITUTED BIPHENYL DERIVATIVES | MERCK PATENT GMBH (DE) | 2001-09-27 | — | — | WO | disclosed |