Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11165200 | 0.77 | ALOX5 (0.36) | HSD17B10TSHR | |
| SCHEMBL2996694 | 0.75 | TSHR (0.35) | MEN1KMT2ATSHRNPSR1 | |
| SCHEMBL11097750 | 0.73 | POLB (0.31) | — | |
| SCHEMBL14227273 | 0.73 | POLB (0.34) | TSHRNPSR1 | |
| SCHEMBL7957203 | 0.70 | POLB (0.30) | — | |
| SCHEMBL7637281 | 0.67 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL5844011 | 0.62 | HSD17B10 (0.46) | SMN1; SMN2HSD17B10MEN1KMT2ATSHR | |
| SCHEMBL7697838 | 0.62 | CYP19A1 (0.35) | MEN1KMT2A | |
| SCHEMBL11242964 | 0.62 | HSD17B10 (0.33) | HSD17B10 | |
| SCHEMBL11423285 | 0.60 | GAA (0.32) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100567268-C | Method by secondary amino group oxide compound amine aether | CIBA SC HOLDING AG (CH) | 2009-12-09 | — | — | CN | disclosed |
| CN-1430605-A | Method for synthesizing amine ethers from secondary amino oxides | CIBA SC HOLDING AG (CH) | 2003-07-16 | — | — | CN | disclosed |
| EP-1282630-A1 | HYDROXYLAMINE ESTERS AS POLYMERIZATION INITIATORS | Ciba SC Holding AG (CH) | 2003-02-12 | — | — | EP | disclosed |
| WO-2001090113-A1 | HYDROXYLAMINE ESTERS AS POLYMERIZATION INITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-11-29 | — | — | WO | disclosed |