Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.97 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.97 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.97 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.97 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.97 |
| ▸ | KDM4A | O75164 | 4/20 | 0.54 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.54 |
| ▸ | INSR | P06213 | 2/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.38 |
| ▸ | CHRNA10 | Q9GZZ6 | 3/20 | 0.38 |
| ▸ | CHRNA9 | Q9UGM1 | 3/20 | 0.38 |
| ▸ | APP | P05067 | 4/20 | 0.38 |
| ▸ | CHAT | P28329 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL29408332 | 0.99 | CHRM2 (1.00) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Bromide SCHEMBL1527120 | 0.99 | CHRM2 (1.00) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL30737946 | 0.96 | CHRM2 (0.91) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Bromide SCHEMBL701716 | 0.95 | CHRM2 (0.93) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL13224060 | 0.94 | CHRM2 (0.86) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Bromide SCHEMBL3420607 | 0.93 | CHRM2 (0.89) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Bromide SCHEMBL3420614 | 0.93 | CHRM2 (0.89) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL13224013 | 0.88 | CHRM2 (0.77) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL14984181 | 0.88 | CHRM2 (0.97) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL10103997 | 0.88 | CHRM2 (0.76) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124357-B2 | Cell comprising exogenous clostridial toxin receptor for use as quality control agents in pharmaceutical and food processing | ALLERGAN, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| US-20080160561-A1 | Lipophilic Dye-Based Fret Assays for Clostridal Toxin Activity | ALLERGAN INC. (US) | 2008-07-03 | — | — | US | disclosed |