Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | CPT2 | P23786 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5705267 | 0.87 | FFAR1 (0.36) | FFAR1CPT2TDP1ACACBACACA | |
| SCHEMBL5705346 | 0.87 | FFAR1 (0.36) | FFAR1CPT2TDP1ACACBACACA | |
| SCHEMBL5705265 | 0.81 | MAPT (0.39) | FFAR1CPT2TDP1ACACBACACA | |
| SCHEMBL5705343 | 0.80 | ALDH1A1 (0.37) | FFAR1CPT2TDP1ACACBACACA | |
| SCHEMBL3278431 | 0.79 | — | — | |
| SCHEMBL5705287 | 0.77 | FFAR1 (0.33) | FFAR1CPT2TDP1 | |
| SCHEMBL7025020 | 0.77 | FFAR1 (0.33) | FFAR1CPT2TDP1 | |
| SCHEMBL5705297 | 0.76 | FFAR1 (0.35) | FFAR1CPT2TDP1ACACBACACA | |
| SCHEMBL5705429 | 0.73 | ALDH1A1 (0.32) | — | |
| SCHEMBL5705433 | 0.72 | CYP4F2 (0.33) | FFAR1CPT2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326822-A2 | KETONE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | Esperion Therapeutics Inc. (US) | 2003-07-16 | — | — | EP | claimed |
| WO-2002030860-A2 | KETONE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2002-04-18 | — | — | WO | claimed |
| WO-2002030860-A9 | KETONE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS INC (US) | 2003-02-20 | — | — | WO | disclosed |