Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Asparagine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.48 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.48 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 5/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.44 |
| ▸ | GSR | P00390 | 2/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.44 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.44 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | GRM8 | O00222 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Asparagine SCHEMBL2162441 | 1.00 | ALOX15 (0.48) | ALOX15BLMPMP22KMT2AGLRA1 | |
| Asparagine SCHEMBL2169164 | 1.00 | ALOX15 (0.48) | ALOX15BLMPMP22KMT2AGLRA1 | |
| Asparagine SCHEMBL547266 | 1.00 | ALOX15 (0.48) | ALOX15BLMPMP22KMT2AGLRA1 | |
| Asparagine SCHEMBL2565048 | 1.00 | ALOX15 (0.48) | ALOX15BLMPMP22KMT2AGLRA1 | |
| Asparagine SCHEMBL17479548 | 1.00 | ALOX15 (0.48) | ALOX15BLMPMP22KMT2AGLRA1 | |
| Asparagine SCHEMBL8128327 | 1.00 | ALOX15 (0.48) | ALOX15BLMPMP22KMT2AGLRA1 | |
| Asparagine SCHEMBL9614916 | 1.00 | ALOX15 (0.48) | ALOX15BLMPMP22KMT2AGLRA1 | |
| Asparagine SCHEMBL153300 | 1.00 | ALOX15 (0.48) | ALOX15BLMPMP22KMT2AGLRA1 | |
| Asparagine SCHEMBL6865127 | 1.00 | ALOX15 (0.48) | ALOX15BLMPMP22KMT2AGLRA1 | |
| Asparagine SCHEMBL18109899 | 1.00 | ALOX15 (0.48) | ALOX15BLMPMP22KMT2AGLRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 694 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337643-A4 | MANIPULATION OF PLANT LIFE CYCLES AND/OR GROWTH PHASES | MOLECULAR PLANT BREEDING NOMINEES LTD (AU) | 2005-08-10 | — | — | EP | claimed |
| EP-1337643-A1 | MANIPULATION OF PLANT LIFE CYCLES AND/OR GROWTH PHASES | Molecular Plant Breeding Nominees Ltd (AU) | 2003-08-27 | — | — | EP | claimed |
| WO-2002038768-A1 | MANIPULATION OF PLANT LIFE CYCLES AND/OR GROWTH PHASES | MOLECULAR PLANT BREEDING NOMINEES LTD (AU) | 2002-05-16 | — | — | WO | claimed |
| CN-112166188-B | Method for producing ethanol using engineered yeast | 嘉吉有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-113785039-B | Polypeptides having beta-glucanase activity, polynucleotides encoding same and use thereof in cleaning and detergent compositions | 诺维信公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-110628729-B | Baculovirus and composition for detecting and preventing porcine epidemic diarrhea virus infection | 周美吟 | 2024-05-28 | — | — | CN | disclosed |
| CN-114621987-B | Method for preparing arabinoxylan with different molecular weight distribution characteristics | 国家粮食和物资储备局科学研究院 | 2024-05-17 | — | — | CN | disclosed |
| CN-117836322-A | Human neutralizing monoclonal antibodies against SARS-CoV-2 and uses thereof | 巴斯德研究所 | 2024-04-05 | — | — | CN | disclosed |
| CN-113881685-B | Gene PpHSP20-like1 for promoting plant organ to produce red color and application thereof | 江苏省农业科学院 | 2024-03-29 | — | — | CN | disclosed |
| CN-111770996-B | Mutant beta-glucosidase | 花王株式会社 | 2024-03-26 | — | — | CN | disclosed |
| CN-110352198-B | CD133 binding agents and uses thereof | 多伦多大学管理委员会 | 2024-03-26 | — | — | CN | disclosed |
| WO-1994008012-A1 | METHODS FOR INCREASING SECRETION OF OVEREXPRESSED PROTEINS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1994-04-14 | — | — | WO | disclosed |
| WO-1994007520-A1 | METHOD OF TREATING RHEUMATOID ARTHRITIS WITH TYPE II COLLAGEN | AUTOIMMUNE, INC. (US) | 1994-04-14 | — | — | WO | disclosed |
| EP-0591263-A1 | METHOD FOR INHIBITING ADHESION OF WHITE BLOOD CELLS TO ENDOTHELIAL CELLS | CHIRON CORPORATION (US) | 1994-04-13 | — | — | EP | disclosed |
| EP-0569527-A1 | INHERITED AND SOMATIC MUTATIONS OF APC GENE IN COLORECTAL CANCER OF HUMANS | THE JOHNS HOPKINS UNIVERSITY (US) | 1993-11-18 | — | — | EP | disclosed |
| EP-0551329-A1 | APROTININ ANALOGUES | NOVO NORDISK A/S (DK) | 1993-07-21 | — | — | EP | disclosed |
| US-5166133-A | Antideposit agents or antiinflammatory agents by administering microglobulins | CETUS CORPORATION (US) | 1992-11-24 | — | — | US | disclosed |
| WO-1992018160-A2 | METHOD FOR INHIBITING ADHESION OF WHITE BLOOD CELLS TO ENDOTHELIAL CELLS | CETUS ONCOLOGY CORPORATION (US) | 1992-10-29 | — | — | WO | disclosed |
| WO-1992013103-A1 | INHERITED AND SOMATIC MUTATIONS OF APC GENE IN COLORECTAL CANCER OF HUMANS | THE JOHNS HOPKINS UNIVERSITY (US) | 1992-08-06 | — | — | WO | disclosed |
| WO-1992006111-A1 | APROTININ ANALOGUES | NOVO NORDISK A/S (DK) | 1992-04-16 | — | — | WO | disclosed |