Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALML3 | P27482 | 6/20 | 0.55 |
| ▸ | MAOA | P21397 | 11/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7837659 | 1.00 | CALML3 (0.55) | CALML3MAOAMAOBCYP2C19CYP3A4 | |
| SCHEMBL8111029 | 0.89 | MAOA (0.57) | CALML3MAOAMAOB | |
| SCHEMBL7846248 | 0.85 | MAOA (0.42) | CALML3MAOAMAOBCYP2C19CYP3A4 | |
| SCHEMBL3758261 | 0.84 | CALML3 (0.55) | CALML3MAOAMAOBCYP2C19CYP3A4 | |
| SCHEMBL7002526 | 0.83 | CALML3 (0.63) | CALML3MAOAMAOBCYP2C19CYP3A4 | |
| SCHEMBL8822058 | 0.78 | MAOA (0.60) | CALML3MAOAMAOB | |
| SCHEMBL5833572 | 0.77 | CALML3 (0.48) | CALML3MAOAMAOBCYP2C19CYP3A4 | |
| SCHEMBL3757473 | 0.77 | CALML3 (0.48) | CALML3MAOAMAOBCYP2C19CYP3A4 | |
| SCHEMBL8102119 | 0.77 | MAOA (0.62) | CALML3MAOAMAOBCYP2C19CYP3A4 | |
| SCHEMBL4753020 | 0.77 | MAOA (0.62) | CALML3MAOAMAOBCYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286998-A1 | OXAZOLIDINONE DERIVATIVES WITH ANTIBIOTIC ACTIVITY | AstraZeneca AB (SE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001081350-A1 | OXAZOLIDINONE DERIVATIVES WITH ANTIBIOTIC ACTIVITY | ASTRAZENECA AB (SE) | 2001-11-01 | — | — | WO | disclosed |
| EP-1034175-A1 | SUBSTITUTED PHENYLOXAZOLIDINONES AND THEIR USE AS ANTIBIOTICS | AstraZeneca UK Limited (GB) | 2000-09-13 | — | — | EP | disclosed |
| EP-1005469-A1 | OXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | ZENECA LIMITED (GB) | 2000-06-07 | — | — | EP | disclosed |
| WO-1999028317-A1 | SUBSTITUTED PHENYLOXAZOLIDINONES AND THEIR USE AS ANTIBIOTICS | ASTRAZENECA UK LIMITED (GB) | 1999-06-10 | — | — | WO | disclosed |
| WO-1999010343-A1 | OXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | ZENECA LIMITED (GB) | 1999-03-04 | — | — | WO | disclosed |