Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28180886 | 0.86 | LMNA (0.31) | LMNA | |
| SCHEMBL2761263 | 0.84 | LMNA (0.46) | LMNA | |
| SCHEMBL10483627 | 0.84 | LMNA (0.40) | LMNA | |
| SCHEMBL28248627 | 0.82 | LMNA (0.50) | LMNA | |
| SCHEMBL3335346 | 0.81 | TSHR (0.36) | — | |
| SCHEMBL14775581 | 0.80 | LMNA (0.39) | LMNA | |
| SCHEMBL4450507 | 0.79 | TSHR (0.37) | — | |
| SCHEMBL9366046 | 0.77 | LMNA (0.39) | LMNA | |
| SCHEMBL3335779 | 0.77 | TSHR (0.41) | — | |
| SCHEMBL6884225 | 0.77 | TSHR (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114685507-B | Purine amine derivative CDK2 inhibitor and preparation method and application thereof | 山东大学 | 2024-01-12 | — | — | CN | disclosed |
| CN-113811302-B | Use of kinase inhibitors | 山东轩竹医药科技有限公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-116041328-A | Process for preparing CDK4/6 kinase inhibitor compounds | 轩竹生物科技股份有限公司 | 2023-05-02 | — | — | CN | disclosed |
| EP-3946230-A1 | METHOD FOR TREATING KERATIN MATERIAL | Henkel AG & Co. KGaA (DE) | 2022-02-09 | — | — | EP | disclosed |
| WO-2020200575-A1 | METHOD FOR TREATING KERATIN MATERIAL | HENKEL AG & CO. KGAA (DE) | 2020-10-08 | — | — | WO | disclosed |
| EP-3259300-B1 | METHOD FOR PRODUCING POLYCARBONATES BY THE TRANSESTERIFICATION OF DITHIOCARBONATES OR THEIR SELENIUM ANALOGUES WITH POLYOLS | COVESTRO DEUTSCHLAND AG (DE) | 2020-09-09 | — | — | EP | disclosed |
| EP-3259300-A1 | METHOD FOR PRODUCING POLYCARBONATES BY TRANSESTERIFICATION OF DITHIOCARBONATES OR THE SELENIUM ANALOGUES THEREOF WITH BISPHENOLS | Covestro Deutschland AG (DE) | 2017-12-27 | — | — | EP | disclosed |
| WO-2016131747-A1 | METHOD FOR PRODUCING POLYCARBONATES BY TRANSESTERIFICATION OF DITHIOCARBONATES OR THE SELENIUM ANALOGUES THEREOF WITH BISPHENOLS | COVESTRO DEUTSCHLAND AG (DE) | 2016-08-25 | — | — | WO | disclosed |
| EP-1343787-A1 | 6-PHENYL-PYRAZOLOPYRIMIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002048151-A1 | 6-PHENYL-PYRAZOLOPYRIMIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2002-06-20 | — | — | WO | disclosed |
| EP-0162208-A2 | Novel N-substituted 3,4-dihydropyrimidine derivatives, processes for preparing them and pharmaceutical compositions | SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD. (JP) | 1985-11-27 | — | — | EP | disclosed |