SCHEMBL7003239

SCHEMBL7003239

[NH]Nc1cccc2c1ccc1ccccc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 4/20 0.58
ALDH1A1 P00352 5/20 0.50
HSD17B10 Q99714 5/20 0.50
TSHR P16473 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
CYP2A6 P11509 1/20 0.50
HPGD P15428 2/20 0.44
CYP3A4 P08684 2/20 0.44
TP53 P04637 1/20 0.44
ALOX15 P16050 1/20 0.44
CDC25B P30305 1/20 0.44
ATM Q13315 1/20 0.44
PAX8 Q06710 1/20 0.43
CYP1A2 P05177 2/20 0.43
HIF1A Q16665 1/20 0.43
CYP1B1 Q16678 1/20 0.43
THRB P10828 1/20 0.43
KDM4E B2RXH2 1/20 0.41
GAA P10253 1/20 0.41
KEAP1 Q14145 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL733945 0.87 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRTDP1CYP2A6
SCHEMBL6541282 0.83 HPRT1 (0.64) HPRT1ALDH1A1HSD17B10TSHRTDP1
SCHEMBL9572742 0.83 HPRT1 (0.64) HPRT1ALDH1A1HSD17B10TSHRTDP1
SCHEMBL21645599 0.81 HPRT1 (0.61) HPRT1ALDH1A1HSD17B10TSHRTDP1
SCHEMBL11873402 0.79 HPRT1 (0.58) HPRT1ALDH1A1HSD17B10TSHRTDP1
SCHEMBL16194255 0.79 HPRT1 (0.58) HPRT1ALDH1A1HSD17B10TSHRTDP1
SCHEMBL28166910 0.79 HPRT1 (0.58) HPRT1ALDH1A1HSD17B10TSHRTDP1
SCHEMBL16194204 0.79 HPRT1 (0.58) HPRT1ALDH1A1HSD17B10TSHRTDP1
SCHEMBL28976146 0.79 ALDH1A1 (0.53) HPRT1ALDH1A1HSD17B10TSHRTDP1
SCHEMBL25510 0.76 HPRT1 (1.00) HPRT1ALDH1A1HSD17B10TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1212134-A4 METALLACROWN ETHER CATALYSTS FOR HYDROFORMYLATION UAB RESEARCH FOUNDATION (US) 2003-01-22 EP claimed
EP-1212134-A1 METALLACROWN ETHER CATALYSTS FOR HYDROFORMYLATION UAB Research Foundation (US) 2002-06-12 EP claimed
WO-2001007156-A1 METALLACROWN ETHER CATALYSTS FOR HYDROFORMYLATION UAB RESEARCH FOUNDATION (US) 2001-02-01 WO claimed