Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.65 |
| ▸ | CA7 | P43166 | 1/20 | 0.65 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 5/20 | 0.56 |
| ▸ | HTR1A | P08908 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TAOK1 | Q7L7X3 | 5/20 | 0.55 |
| ▸ | TAOK3 | Q9H2K8 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11450707 | 0.93 | CA12 (0.58) | CA12CA7CA14MEN1KMT2A | |
| SCHEMBL11442868 | 0.93 | CA12 (0.58) | CA12CA7CA14MEN1KMT2A | |
| SCHEMBL14335327 | 0.92 | MEN1 (0.69) | MEN1KMT2ADRD2HTR1AALDH1A1 | |
| SCHEMBL14336032 | 0.92 | MEN1 (0.69) | MEN1KMT2ADRD2HTR1AALDH1A1 | |
| SCHEMBL14376708 | 0.92 | MEN1 (0.69) | MEN1KMT2ADRD2HTR1AALDH1A1 | |
| SCHEMBL14376821 | 0.92 | MEN1 (0.69) | MEN1KMT2ADRD2HTR1AALDH1A1 | |
| SCHEMBL11178224 | 0.92 | CA12 (0.57) | CA12CA7CA14MEN1KMT2A | |
| SCHEMBL11355077 | 0.92 | CA12 (0.57) | CA12CA7CA14MEN1KMT2A | |
| SCHEMBL5969969 | 0.92 | ALDH1A1 (0.61) | MEN1KMT2ADRD2HTR1AALDH1A1 | |
| SCHEMBL5970025 | 0.92 | ALDH1A1 (0.61) | MEN1KMT2ADRD2HTR1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066039-A4 | SUBSTITUTED QUINAZOLINES AND ANALOGS AND THE USE THEREOF | COCENSYS INC (US) | 2003-02-26 | — | — | EP | disclosed |
| EP-1066039-A1 | SUBSTITUTED QUINAZOLINES AND ANALOGS AND THE USE THEREOF | Cocensys, Inc. (US) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999044612-A1 | SUBSTITUTED QUINAZOLINES AND ANALOGS AND THE USE THEREOF | COCENSYS, INC. (US) | 1999-09-10 | — | — | WO | disclosed |