Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25079138 | 0.83 | — | — | |
| SCHEMBL14067377 | 0.81 | — | — | |
| SCHEMBL554111 | 0.78 | ALDH1A1 (0.48) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL21500725 | 0.78 | CA12 (0.43) | ALDH1A1LMNAHSD17B10CA12CA1 | |
| SCHEMBL10312391 | 0.78 | — | — | |
| SCHEMBL1544765 | 0.78 | — | — | |
| SCHEMBL5462451 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL2935026 | 0.76 | ALDH1A1 (0.46) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL10519040 | 0.76 | — | — | |
| SCHEMBL15152362 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7361644-B2 | Specific antagonist for both E- and P-selectins | GLYCOMIMETICS, INC. (US) | 2008-04-22 | — | — | US | disclosed |
| EP-1763533-B1 | SPECIFIC ANTAGONIST FOR BOTH E- AND P-SELECTINS | GLYCOMIMETICS INC (US) | 2008-01-09 | — | — | EP | disclosed |
| EP-1189889-B1 | COMPOSITIONS AND METHODS FOR INHIBITING CELL DEATH | ELAN PHARMA INT LTD (IE) | 2003-12-17 | — | — | EP | disclosed |
| US-6541486-B1 | Used for treating ischemia, such as results from stroke or myocardial infarction, trauma, neurodegeneration, and inflammation. | ELAN PHARMA INTERNATIONAL LTD. (IE) | 2003-04-01 | — | — | US | disclosed |