Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | CDC25B | P30305 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | MAOA | P21397 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | PTPRC | P08575 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | APAF1 | O14727 | 2/20 | 0.39 |
| ▸ | TDP2 | O95551 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | S100A4 | P26447 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL737866 | 0.88 | MAOA (0.41) | MEN1KMT2ACDC25BMAPTMAOA | |
| SCHEMBL787044 | 0.72 | CDC25B (0.55) | MEN1KMT2ACDC25BMAPTMAOA | |
| SCHEMBL11882418 | 0.71 | MEN1 (0.55) | MEN1KMT2ACDC25BMAPTMAOA | |
| SCHEMBL2385124 | 0.69 | — | — | |
| SCHEMBL5494021 | 0.69 | CDC25B (0.41) | MEN1KMT2ACDC25BMAPTMAOA | |
| SCHEMBL1501865 | 0.69 | CDC25B (0.41) | MEN1KMT2ACDC25BMAPTMAOA | |
| SCHEMBL14003716 | 0.68 | CDC25B (0.73) | MEN1KMT2ACDC25BMAPTMAOA | |
| SCHEMBL5393525 | 0.68 | — | — | |
| Anthraquinone SCHEMBL29358690 | 0.68 | MEN1 (1.00) | MEN1KMT2ACDC25BMAPTMAOA | |
| Anthraquinone SCHEMBL1901249 | 0.68 | MEN1 (1.00) | MEN1KMT2ACDC25BMAPTMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313736-A2 | CONDENSED PYRAZINDIONE DERIVATIVES | Lilly Icos LLC (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002000657-A2 | CONDENSED PYRAZINDIONE DERIVATIVES | LILLY ICOS LLC (US) | 2002-01-03 | — | — | WO | disclosed |