Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | CHRNA7 | P36544 | 10/20 | 0.58 |
| ▸ | HTR3A | P46098 | 2/20 | 0.52 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.48 |
| ▸ | HTR3B | O95264 | 1/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4207651 | 0.96 | ALDH1A1 (0.65) | ALDH1A1POLBCHRNA7HTR3AHTR3E | |
| SCHEMBL4207653 | 0.96 | ALDH1A1 (0.65) | ALDH1A1POLBCHRNA7HTR3AHTR3E | |
| SCHEMBL4202120 | 0.83 | ALDH1A1 (0.72) | ALDH1A1POLBCHRNA7HTR3AHTR3E | |
| SCHEMBL4198172 | 0.83 | ALDH1A1 (0.72) | ALDH1A1POLBCHRNA7HTR3AHTR3E | |
| SCHEMBL7003179 | 0.82 | ALDH1A1 (0.55) | ALDH1A1POLBCHRNA7HTR3AHTR3E | |
| SCHEMBL7061174 | 0.82 | ALDH1A1 (0.68) | ALDH1A1POLBCHRNA7HTR3AHTR3E | |
| SCHEMBL7121903 | 0.82 | ALDH1A1 (0.57) | ALDH1A1POLBCHRNA7HTR3AHTR3E | |
| SCHEMBL7062183 | 0.81 | ALDH1A1 (0.67) | ALDH1A1POLBCHRNA7HTR3AHTR3E | |
| SCHEMBL7123520 | 0.81 | CHRNA7 (0.66) | ALDH1A1POLBCHRNA7HTR3AHTR3E | |
| SCHEMBL7059425 | 0.81 | ALDH1A1 (0.59) | ALDH1A1POLBCHRNA7HTR3AHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1259508-B1 | NOVEL BIARYLCARBOXAMIDES | ASTRAZENECA AB (SE) | 2003-10-15 | — | — | EP | disclosed |