Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.73 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.62 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.62 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21883722 | 0.87 | RAPGEF4 (0.67) | GAAAKR1C3AKR1C2RAPGEF4ACHE | |
| SCHEMBL502786 | 0.85 | GAA (1.00) | GAAAKR1C3AKR1C2SMN1; SMN2NPC1 | |
| SCHEMBL10912994 | 0.83 | GAA (0.51) | GAAAKR1C3AKR1C2SMN1; SMN2NPC1 | |
| SCHEMBL5608725 | 0.83 | NPSR1 (0.59) | GAAAKR1C3AKR1C2RAPGEF4SMN1; SMN2 | |
| SCHEMBL9479715 | 0.82 | GAA (0.93) | GAAAKR1C3AKR1C2SMN1; SMN2NPC1 | |
| SCHEMBL6999192 | 0.81 | GAA (0.75) | GAAAKR1C3AKR1C2ACHESMN1; SMN2 | |
| SCHEMBL4230288 | 0.81 | GAA (0.64) | GAARAPGEF4ACHESMN1; SMN2ADRA2A | |
| SCHEMBL25634740 | 0.81 | GAA (0.80) | GAAAKR1C3AKR1C2SMN1; SMN2NPC1 | |
| SCHEMBL9594507 | 0.81 | AKR1C3 (0.82) | GAAAKR1C3AKR1C2SMN1; SMN2NPC1 | |
| SCHEMBL7004055 | 0.81 | GAA (0.64) | GAAAKR1C3AKR1C2RAPGEF4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6635602-B1 | Heat sensitive and pressure sensitive recording material; synthesised directly by the reaction of two derivatives of amino phenols, phthalic anhydrides, keto acids and/or diphenylamines with a phenol derivative | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-10-21 | — | — | US | disclosed |
| US-6566302-B1 | For use in heat sensitive and pressure sensitive recording materials | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-05-20 | — | — | US | disclosed |
| EP-1107972-B1 | PREPARATION PROCESS FOR MANUFACTURE AND PURIFICATION OF MIXTURES OF FLUORAN COMPOUNDS AND RECORDING MATERIAL COMPRISING SAID MIXTURES OF FLUORAN | CIBA SC HOLDING AG (CH) | 2003-01-02 | — | — | EP | disclosed |
| EP-1115579-B1 | MONOPHASE SOLID SOLUTIONS COMPRISING A PLURALITY OF COLOUR FORMER COMPOUNDS AND PROCESS FOR THEIR PREPARATION | CIBA SC HOLDING AG (CH) | 2002-11-20 | — | — | EP | disclosed |
| EP-1115579-A1 | MONOPHASE SOLID SOLUTIONS COMPRISING A PLURALITY OF COLOUR FORMER COMPOUNDS AND PROCESS FOR THEIR PREPARATION | Ciba SC Holding AG (CH) | 2001-07-18 | — | — | EP | disclosed |
| EP-1107972-A1 | PREPARATION PROCESS FOR MANUFACTURE AND PURIFICATION OF MIXTURES OF FLUORAN COMPOUNDS AND RECORDING MATERIAL COMPRISING SAID MIXTURES OF FLUORAN | Ciba SC Holding AG (CH) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000026037-A1 | HEAT SENSITIVE RECORDING MATERIAL | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-05-11 | — | — | WO | disclosed |
| WO-2000012318-A1 | MONOPHASE SOLID SOLUTIONS COMPRISING A PLURALITY OF COLOUR FORMER COMPOUNDS AND PROCESS FOR THEIR PREPARATION | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-03-09 | — | — | WO | disclosed |
| WO-2000012513-A1 | NOVEL PREPARATION PROCESS FOR MANUFACTURE AND PURIFICATION OF MIXTURES OF FLUORAN COMPOUNDS AND RECORDING MATERIAL COMPRISING SAID MIXTURES OF FLUORAN COMPOUNDS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-03-09 | — | — | WO | disclosed |
| EP-0546577-B1 | Crystal modification of 2-(3-methylanilino)-3-methyl-6-diethylaminofluoran, process for the preparation thereof, and recording materials containing said crystal modification | YAMAMOTO CHEMICALS INC (JP) | 1996-10-16 | — | — | EP | disclosed |
| EP-0526856-B1 | Crystal modifications of 2-m-toluidino-3-methyl-6-di-n-butylaminofluoran, process for preparing thereof, and recording materials containing said crystal modifications | YAMAMOTO CHEMICALS INC (JP) | 1996-10-16 | — | — | EP | disclosed |
| US-5438032-A | Electron donating color former containing alpha-type crystals for reacting with electron accepting color developer to form image; solvent solubility, storage stability, color rendition, colorfastness | YAMAMOTO CHEMICALS, INC. (JP) | 1995-08-01 | — | — | US | disclosed |
| US-5376617-A | Heat sensitive, pressure sensitive recording material | YAMAMOTO CHEMICALS, INC. (JP) | 1994-12-27 | — | — | US | disclosed |
| US-5342967-A | Solubility | YAMAMOTO CHEMICALS, INC. (JP) | 1994-08-30 | — | — | US | disclosed |
| US-5338866-A | Reacting 2-(2-hydroxy-4-diethylaminobenzoyl)benzoic acid with 2,3'-dimethyl-4-alkoxydiphenylamine in presence of condensing/ dehydrating agent | YAMAMOTO CHEMICALS, INC. (JP) | 1994-08-16 | — | — | US | disclosed |
| EP-0546577-A1 | Crystal modification of 2-(3-methylanilino)-3-methyl-6-diethylaminofluoran, process for the preparation thereof, and recording materials containing said crystal modification | Yamamoto Chemicals, Inc. (JP) | 1993-06-16 | — | — | EP | disclosed |
| EP-0526856-A2 | Crystal modifications of 2-m-toluidino-3-methyl-6-di-n-butylaminofluoran, process for preparing thereof, and recording materials containing said crystal modifications | Yamamoto Chemicals, Inc. (JP) | 1993-02-10 | — | — | EP | disclosed |