Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A1 | P53985 | 20/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.42 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.42 |
| ▸ | SLC16A7 | O60669 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7011954 | 0.99 | SLC16A1 (0.43) | SLC16A1CYP2C9MAPKAPK2CAMK2BHIPK4 | |
| SCHEMBL7004038 | 0.98 | SLC16A1 (0.42) | SLC16A1CYP2C9MAPKAPK2CAMK2BHIPK4 | |
| Lithium Ion SCHEMBL7004041 | 0.89 | SLC16A1 (0.42) | SLC16A1CYP2C9MAPKAPK2CAMK2BHIPK4 | |
| Lithium SCHEMBL7977772 | 0.84 | SLC16A1 (0.47) | SLC16A1CYP2C9MAPKAPK2CAMK2BHIPK4 | |
| SCHEMBL7991784 | 0.83 | SLC16A1 (0.47) | SLC16A1CYP2C9MAPKAPK2CAMK2BHIPK4 | |
| SCHEMBL7977767 | 0.82 | SLC16A1 (0.47) | SLC16A1CYP2C9MAPKAPK2CAMK2BHIPK4 | |
| SCHEMBL7012735 | 0.81 | SLC16A1 (0.62) | SLC16A1CYP2C9MAPKAPK2CAMK2BHIPK4 | |
| SCHEMBL7007756 | 0.81 | SLC16A1 (0.46) | SLC16A1CYP2C9MAPKAPK2CAMK2BHIPK4 | |
| SCHEMBL7007887 | 0.80 | SLC16A1 (0.49) | SLC16A1CYP2C9MAPKAPK2CAMK2BHIPK4 | |
| SCHEMBL7006688 | 0.80 | SLC16A1 (0.45) | SLC16A1CYP2C9MAPKAPK2CAMK2BHIPK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107973-B1 | NOVEL THIENO[2,3-d]PYRIMIDINEDIONES, PROCESS FOR THEIR PREPARATION AND USE THEREOF IN THERAPY | ASTRAZENECA AB (SE) | 2003-11-05 | — | — | EP | disclosed |
| EP-1107973-A1 | NOVEL COMPOUNDS | AstraZeneca AB (SE) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012514-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2000-03-09 | — | — | WO | disclosed |