Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31346513 | 0.82 | ALDH1A1 (0.58) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL3972303 | 0.82 | ALDH1A1 (0.58) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL6542106 | 0.80 | ALDH1A1 (0.56) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL733945 | 0.79 | ALDH1A1 (0.56) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL31067901 | 0.78 | ALDH1A1 (0.55) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL28839837 | 0.78 | ALDH1A1 (0.55) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL577961 | 0.78 | ALDH1A1 (0.55) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL6626253 | 0.78 | ALDH1A1 (0.59) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL4985918 | 0.78 | KDM4E (0.64) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL10421492 | 0.77 | ALDH1A1 (0.53) | ALDH1A1KDM4EGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212134-A4 | METALLACROWN ETHER CATALYSTS FOR HYDROFORMYLATION | UAB RESEARCH FOUNDATION (US) | 2003-01-22 | — | — | EP | claimed |
| EP-1212134-A1 | METALLACROWN ETHER CATALYSTS FOR HYDROFORMYLATION | UAB Research Foundation (US) | 2002-06-12 | — | — | EP | claimed |
| WO-2001007156-A1 | METALLACROWN ETHER CATALYSTS FOR HYDROFORMYLATION | UAB RESEARCH FOUNDATION (US) | 2001-02-01 | — | — | WO | claimed |
| US-6579997-B1 | Enhanced activity of metal complexes | UAB RESEARCH FOUNDATION | 2003-06-17 | — | — | US | disclosed |