Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8611258 | 0.78 | ELANE (0.63) | ELANE | |
| SCHEMBL8616353 | 0.77 | ELANE (0.63) | ELANE | |
| SCHEMBL8616013 | 0.76 | ELANE (0.61) | ELANE | |
| SCHEMBL7276065 | 0.76 | ELANE (0.71) | ELANE | |
| SCHEMBL9010433 | 0.75 | ELANE (0.74) | ELANE | |
| SCHEMBL7305972 | 0.74 | ELANE (0.68) | ELANE | |
| SCHEMBL8609841 | 0.74 | ELANE (0.60) | ELANE | |
| SCHEMBL7278147 | 0.74 | ELANE (0.69) | ELANE | |
| SCHEMBL8609098 | 0.73 | ELANE (0.60) | ELANE | |
| SCHEMBL7004780 | 0.73 | ELANE (0.66) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0547708-B1 | Saccharin derivative proteolytic enzyme inhibitors | SANOFI SYNTHELABO (FR) | 2003-02-26 | — | — | EP | disclosed |
| EP-0626378-B1 | Saccharin derivative proteolytic enzyme inhibitors | SANOFI SYNTHELABO (FR) | 2003-01-22 | — | — | EP | disclosed |
| US-5466701-A | Degenerative diseases | STERLING WINTHROP INC. (US) | 1995-11-14 | — | — | US | disclosed |
| US-5378720-A | Treatment of rheumatoid arthritis, emphysema, pancreatitis | STERLING WINTHROP INC. (US) | 1995-01-03 | — | — | US | disclosed |
| EP-0626378-A1 | Saccharin derivative proteolytic enzyme inhibitors | STERLING WINTHROP INC. (US) | 1994-11-30 | — | — | EP | disclosed |
| EP-0547708-A1 | Saccharin derivative proteolytic enzyme inhibitors | STERLING WINTHROP INC. (US) | 1993-06-23 | — | — | EP | disclosed |