Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 12/20 | 0.41 |
| ▸ | FPR3 | P25089 | 1/20 | 0.38 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | MLNR | O43193 | 2/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7001642 | 0.85 | GRM2 (0.41) | CCR1FPR3GPR65GPR35S1PR5 | |
| SCHEMBL7004493 | 0.84 | PTGER4 (0.43) | CCR1FPR3GPR65GPR35S1PR5 | |
| SCHEMBL6996220 | 0.83 | CCR1 (0.43) | CCR1FPR3GPR65GPR35S1PR5 | |
| SCHEMBL6999918 | 0.80 | CCR1 (0.40) | CCR1FPR3GPR65GPR35S1PR5 | |
| SCHEMBL7002094 | 0.79 | CCR1 (0.47) | CCR1FPR3GPR65GPR35S1PR5 | |
| SCHEMBL6999003 | 0.79 | CCR1 (0.41) | CCR1FPR3GPR65GPR35S1PR5 | |
| SCHEMBL6995002 | 0.77 | CCR1 (0.44) | CCR1FPR3GPR65GPR35PTGDR2 | |
| SCHEMBL6999933 | 0.76 | MEN1 (0.37) | CCR1PTGER4PTGER2 | |
| SCHEMBL7001654 | 0.76 | CCR1 (0.38) | CCR1FPR3GPR65GPR35S1PR5 | |
| SCHEMBL6997000 | 0.75 | CCR1 (0.49) | CCR1FPR3GPR65GPR35S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326867-A2 | BRIDGED PIPERAZINE DERIVATIVES | Pfizer Products Inc. (US) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002032901-A2 | BRIDGED PIPERAZINE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2002-04-25 | — | — | WO | disclosed |