Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.47 |
| ▸ | RAB9A | P51151 | 10/20 | 0.47 |
| ▸ | AR | P10275 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TERT | O14746 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7004097 | 0.89 | NPC1 (0.46) | NPC1RAB9AARCYP3A4CYP1A2 | |
| SCHEMBL61467 | 0.86 | NPC1 (0.56) | NPC1RAB9AARCYP3A4CYP1A2 | |
| SCHEMBL7005582 | 0.84 | NPC1 (0.44) | NPC1RAB9AARCYP3A4CYP1A2 | |
| SCHEMBL7004636 | 0.82 | RAB9A (0.51) | NPC1RAB9AARCYP3A4CYP1A2 | |
| SCHEMBL7004662 | 0.77 | AR (0.41) | NPC1RAB9AARCYP1A2SMN1; SMN2 | |
| SCHEMBL7004513 | 0.77 | AR (0.50) | NPC1RAB9AARSMN1; SMN2KDM4E | |
| SCHEMBL8738496 | 0.75 | NPC1 (0.50) | NPC1RAB9AARCYP3A4CYP1A2 | |
| SCHEMBL6490626 | 0.73 | NPC1 (0.50) | NPC1RAB9AARCYP3A4CYP1A2 | |
| SCHEMBL7007827 | 0.73 | NPC1 (0.49) | NPC1RAB9AARCYP3A4CYP1A2 | |
| SCHEMBL10079213 | 0.73 | NPC1 (0.59) | NPC1RAB9AARCYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064499-A1 | PHOSPHORESCENT MATERIALS | UNIVERSAL DISPLAY CORPORATION (US) | 2012-05-18 | — | — | WO | disclosed |