Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TOP1 | P11387 | 9/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 4/20 | 0.40 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7012951 | 0.92 | KDM4E (0.45) | KDM4ETOP1ALDH1A1TOP2ATOP2B | |
| SCHEMBL7009430 | 0.89 | KDM4E (0.53) | KDM4ETOP1ALDH1A1TOP2ATOP2B | |
| SCHEMBL7004815 | 0.88 | KDM4E (0.52) | KDM4ETOP1ALDH1A1TOP2ATOP2B | |
| SCHEMBL7005857 | 0.88 | KDM4E (0.56) | KDM4ETOP1ALDH1A1TOP2ATOP2B | |
| SCHEMBL7015679 | 0.86 | KDM4E (0.50) | KDM4ETOP1ALDH1A1TOP2ATOP2B | |
| SCHEMBL7006455 | 0.85 | KDM4E (0.43) | KDM4ETOP1ALDH1A1TOP2ATOP2B | |
| SCHEMBL7012229 | 0.84 | TOP2A (0.57) | KDM4EALDH1A1TOP2ATOP2BKCNH2 | |
| SCHEMBL7009844 | 0.83 | PIM1 (0.46) | KDM4ETOP1ALDH1A1TOP2ATOP2B | |
| SCHEMBL7005558 | 0.83 | KDM4E (0.43) | KDM4ETOP1ALDH1A1TOP2ATOP2B | |
| SCHEMBL7009159 | 0.83 | CYP3A4 (0.45) | KDM4ETOP1ALDH1A1TOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775702-B1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-5935952-A | ANTIBACTERIAL AGENT | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0775702-A1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 1997-05-28 | — | — | EP | disclosed |