Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TOP2A | P11388 | 6/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TOP1 | P11387 | 5/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7010036 | 0.91 | KDM4E (0.46) | KDM4EALDH1A1TOP2ATOP2BCHRM1 | |
| SCHEMBL7005857 | 0.91 | KDM4E (0.56) | KDM4EALDH1A1TOP2ATOP2BCHRM1 | |
| SCHEMBL7004815 | 0.89 | KDM4E (0.52) | KDM4EALDH1A1TOP2ATOP2BTOP1 | |
| SCHEMBL7013895 | 0.87 | KDM4E (0.55) | KDM4EALDH1A1TOP2ATOP2BCHRM1 | |
| SCHEMBL7004763 | 0.86 | KDM4E (0.50) | KDM4EALDH1A1TOP2ATOP2BTOP1 | |
| SCHEMBL7007995 | 0.83 | TOP2A (0.60) | KDM4EALDH1A1TOP2ATOP2BCHRM1 | |
| SCHEMBL7011692 | 0.83 | LMNA (0.47) | KDM4EALDH1A1TOP2ATOP2BHPGD | |
| SCHEMBL7014477 | 0.82 | TOP2A (0.48) | KDM4EALDH1A1TOP2ATOP2BHPGD | |
| SCHEMBL7010327 | 0.82 | TOP2A (0.46) | KDM4EALDH1A1TOP2ATOP2BCHRM1 | |
| SCHEMBL8322753 | 0.82 | TOP2A (0.46) | KDM4EALDH1A1TOP2ATOP2BCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775702-B1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-5935952-A | ANTIBACTERIAL AGENT | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0775702-A1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 1997-05-28 | — | — | EP | disclosed |