SCHEMBL7004764

SCHEMBL7004764

CC(C)NC1=NSc2sc(Cl)cc2N1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ABCC8 Q09428 1/20 0.31
KCNJ11 Q14654 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7069047 0.88
SCHEMBL7067998 0.86 ABCC8 (0.33) ABCC8KCNJ11
SCHEMBL7069196 0.86 ABCC8 (0.33) ABCC8KCNJ11
SCHEMBL7067993 0.86 ABCC8 (0.33) ABCC8KCNJ11
SCHEMBL7168375 0.85
SCHEMBL7068579 0.85
SCHEMBL7171572 0.84 ABCC8 (0.32) ABCC8KCNJ11
SCHEMBL7067549 0.84
SCHEMBL7066031 0.83 HTT (0.37)
SCHEMBL7066375 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003105896-A1 COMBINED USE OF A MODULATOR OF CD3 AND A BETA CELL RESTING COMPOUND NOVO NORDISK A/S (DK) 2003-12-24 WO claimed
EP-1345947-A1 A NEW PROCESS FOR PREPARING FUSED 1,2,4-THIADIAZINE DERIVATIVES NOVO NORDISK A/S (DK) 2003-09-24 EP claimed
WO-2003045954-A1 USE OF SELECTIVE POTASSIUM CHANNEL OPENERS NOVO NORDISK A/S (DK) 2003-06-05 WO claimed
WO-2003045955-A1 USE OF SELECTIVE POTASSIUM CHANNEL OPENERS NOVO NORDISK A/S (DK) 2003-06-05 WO claimed
WO-2002050085-A1 A NEW PROCESS FOR PREPARING FUSED 1,2,4-THIADIAZINE DERIVATIVES NOVO NORDISK A/S (DK) 2002-06-27 WO claimed
WO-2002000222-A1 USE OF POTASSIUM CHANNEL AGONISTS FOR THE TREATMENT OF CANCER NOVO NORDISK A/S (DK) 2002-01-03 WO claimed
WO-2002000665-A1 USE OF POTASSIUM CHANNEL OPENERS FOR THE TREATMENT OF INSULITIS NOVO NORDISK A/S (DK) 2002-01-03 WO claimed
WO-2002000223-A1 USE OF POTASSIUM CHANNEL AGONISTS FOR REDUCING FAT FOOD COMSUMPTION NOVO NORDISK A/S (DK) 2002-01-03 WO claimed
EP-0876379-A1 FUSED 1,2,4-THIADIAZINE AND FUSED 1,4-THIAZINE DERIVATIVES, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1998-11-11 EP claimed
WO-1997026265-A1 FUSED 1,2,4-THIADIAZINE AND FUSED 1,4-THIAZINE DERIVATIVES, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1997-07-24 WO claimed
CN-1158290-C Fused 1,2,4-thiadiazine and fused 1,4-thiazine derivatives, their preparation and use ŵ��Ų�ڿ˹�˾ 2004-07-21 CN disclosed
WO-2003105896-A1 COMBINED USE OF A MODULATOR OF CD3 AND A BETA CELL RESTING COMPOUND NOVO NORDISK A/S (DK) 2003-12-24 WO disclosed
EP-1345947-A1 A NEW PROCESS FOR PREPARING FUSED 1,2,4-THIADIAZINE DERIVATIVES NOVO NORDISK A/S (DK) 2003-09-24 EP disclosed
WO-2003045954-A1 USE OF SELECTIVE POTASSIUM CHANNEL OPENERS NOVO NORDISK A/S (DK) 2003-06-05 WO disclosed
WO-2003045955-A1 USE OF SELECTIVE POTASSIUM CHANNEL OPENERS NOVO NORDISK A/S (DK) 2003-06-05 WO disclosed
EP-1000066-A1 FUSED 1,2,4-THIADIAZINE DERIVATIVES, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 2000-05-17 EP disclosed
CN-1208417-A Fused 1,2,4-thiadiazine and fused 1,4-thiazine derivatives, their preparation and use NOVO NORDISK AS (DK) 1999-02-17 CN disclosed
WO-1999003861-A1 FUSED 1,2,4-THIADIAZINE DERIVATIVES, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1999-01-28 WO disclosed
EP-0876379-A1 FUSED 1,2,4-THIADIAZINE AND FUSED 1,4-THIAZINE DERIVATIVES, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1998-11-11 EP disclosed
WO-1997026265-A1 FUSED 1,2,4-THIADIAZINE AND FUSED 1,4-THIAZINE DERIVATIVES, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1997-07-24 WO disclosed