Sulfotep

Sulfotep

SCHEMBL7004800

CCOP(=S)(OCC)OP(=S)(OCC)OCC.[NaH]

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
TSHR P16473 7/20 0.38
TP53 P04637 2/20 0.35
ALDH1A1 P00352 7/20 0.34
HSD17B10 Q99714 5/20 0.34
CYP3A4 P08684 4/20 0.34
MAPT P10636 3/20 0.34
MAPK1 P28482 2/20 0.34
ALOX15 P16050 1/20 0.34
ALOX12 P18054 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
KDM4E B2RXH2 2/20 0.33
POLB P06746 1/20 0.33
PPARD Q03181 1/20 0.33
GAA P10253 1/20 0.32
ACHE P22303 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfotep SCHEMBL8191946 0.97 TDP1 (0.46) TDP1MEN1KMT2ATSHRTP53
Sulfotep SCHEMBL35637 0.97 TDP1 (0.46) TDP1MEN1KMT2ATSHRTP53
Sulfotep SCHEMBL1668626 0.94 TDP1 (0.44) TDP1MEN1KMT2ATSHRTP53
Sulfotep SCHEMBL6676271 0.94 TDP1 (0.44) TDP1MEN1KMT2ATSHRTP53
Sulfotep SCHEMBL8336123 0.94 TDP1 (0.44) TDP1MEN1KMT2ATSHRTP53
Sulfotep SCHEMBL21060526 0.94 TDP1 (0.44) TDP1MEN1KMT2ATSHRTP53
Sulfotep SCHEMBL22721240 0.94 TSHR (0.45) TDP1MEN1KMT2ATSHRTP53
Sulfotep SCHEMBL10606468 0.94 TDP1 (0.44) TDP1MEN1KMT2ATSHRTP53
Sulfotep SCHEMBL19510253 0.94 TDP1 (0.44) TDP1MEN1KMT2ATSHRTP53
Sulfotep SCHEMBL6047089 0.94 TDP1 (0.44) TDP1MEN1KMT2ATSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3356356-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 Senomyx, Inc. (US) 2018-08-08 EP disclosed
CN-103842448-A Method for reducing indigo UNIV NAT CHONNAM IND FOUND 2014-06-04 CN disclosed
EP-1267810-A2 METHOD FOR COLOURING HAIR THE PROCTER & GAMBLE COMPANY (US) 2003-01-02 EP disclosed
WO-2001076546-A2 METHOD FOR COLOURING HAIR THE PROCTER & GAMBLE COMPANY (US) 2001-10-18 WO disclosed
US-5837162-A CYCLIC ETHERS FOR LIQUID CRYSTAL DISPLAYS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1998-11-17 US disclosed
EP-0801971-A1 WASTE GAS AND DUST TREATMENT METHOD KANEKA CORPORATION (JP) 1997-10-22 EP disclosed
US-5626793-A Liquid-crystalline compounds MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1997-05-06 US disclosed
EP-0308719-A1 Method for production of hydroxylammonium salt SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-03-29 EP disclosed
EP-0241140-A1 Assay method with a multivalently labelled reagent, and means therefor BioCarb AB (SE) 1987-10-14 EP disclosed
US-4199472-A SODIUM DITHIONITE AND FIBERS MITSUBISHI GAS CHEMICAL COMPANY INC. (JP) 1980-04-22 US disclosed