Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL6718528 | 0.95 | TDP1 (0.62) | TDP1HTTALDH1A1MAPTKMT2A | |
| SCHEMBL2084753 | 0.88 | HTT (0.67) | TDP1HTTALDH1A1MAPTKMT2A | |
| SCHEMBL29469600 | 0.87 | TDP1 (0.64) | TDP1HTTALDH1A1MAPTKMT2A | |
| SCHEMBL397794 | 0.87 | TDP1 (0.64) | TDP1HTTALDH1A1MAPTKMT2A | |
| SCHEMBL11428399 | 0.86 | TDP1 (0.59) | TDP1HTTALDH1A1MAPTKMT2A | |
| SCHEMBL11207238 | 0.86 | TDP1 (0.67) | TDP1HTTALDH1A1MAPTKMT2A | |
| SCHEMBL11233176 | 0.86 | TDP1 (0.67) | TDP1HTTALDH1A1MAPTKMT2A | |
| SCHEMBL700418 | 0.86 | TDP1 (0.62) | TDP1HTTALDH1A1MAPTKMT2A | |
| SCHEMBL11428124 | 0.85 | TDP1 (0.57) | TDP1HTTALDH1A1MAPTKMT2A | |
| SCHEMBL11232774 | 0.85 | TDP1 (0.65) | TDP1HTTALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430967-A | High-dispersity permanent orange RN and preparation method and application thereof | 济宁阳光化学有限公司 | 2024-01-23 | — | — | CN | claimed |
| CN-118026974-A | Chromonol containing difuran diamine structure and disazo pigment derived from same | 江苏丽王科技有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-117430967-A | High-dispersity permanent orange RN and preparation method and application thereof | 济宁阳光化学有限公司 | 2024-01-23 | — | — | CN | disclosed |
| EP-3991752-A1 | CELL-BINDING MOLECULE-TUBULYSIN DERIVATIVE CONJUGATE AND PREPARATION METHOD THEREFOR | Hangzhou Dac Biotech Co., Ltd (CN) | 2022-05-04 | — | — | EP | disclosed |
| CN-108473484-B | Compounds useful as TRPM8 modulators | 弗门尼舍公司 | 2021-06-29 | — | — | CN | disclosed |
| EP-3356356-B1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | FIRMENICH INCORPORATED (US) | 2021-05-26 | — | — | EP | disclosed |
| US-10392371-B2 | Compounds useful as modulators of TRPM8 | SENOMYX, INC. (US) | 2019-08-27 | — | — | US | disclosed |
| US-20190177308-A9 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. | 2019-06-13 | — | — | US | disclosed |
| US-20180273517-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX INC (US) | 2018-09-27 | — | — | US | disclosed |
| US-9732071-B2 | Compounds useful as modulators of TRPM8 | SENOMYX, INC. (US) | 2017-08-15 | — | — | US | disclosed |
| EP-0296597-B1 | Hexa-cyclic compound | DAIICHI SEIYAKU CO (JP) | 1994-09-21 | — | — | EP | disclosed |
| US-5061795-A | ANTITUMOR AGENTS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1991-10-29 | — | — | US | disclosed |
| US-4939255-A | Hexa-cyclic camptothecin derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1990-07-03 | — | — | US | disclosed |
| EP-0296597-A2 | Hexa-cyclic compound | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1988-12-28 | — | — | EP | disclosed |
| US-4591634-A | GOOD BUILD-UP CAPACITY AND COMBINABILITY | BAYER AKTIENGESELLSCHAFT (DE) | 1986-05-27 | — | — | US | disclosed |
| US-4420637-A | HAIR DYES, OXIDATION | L'OREAL (FR) | 1983-12-13 | — | — | US | disclosed |
| EP-0043439-B1 | MIXED TRISAZO/AZOXY DYESTUFFS, THEIR PREPARATION AND USE | BAYER AG (DE) | 1983-07-20 | — | — | EP | disclosed |
| EP-0043439-A2 | Mixed trisazo/azoxy dyestuffs, their preparation and use | BAYER AG (DE) | 1982-01-13 | — | — | EP | disclosed |
| US-4026663-A | Polyester fabric dyed with monoazo dyestuffs | AMERICAN COLOR & CHEMICAL CORPORATION (US) | 1977-05-31 | — | — | US | disclosed |
| US-3941560-A | Trisazo polyester materials | AMERICAN ANILINE PRODUCTS, INC. (US) | 1976-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10392371-B2 | Compounds useful as modulators of TRPM8 | TRPM8, TRPM4, TRPM6 | TDP1 3125/4885HTT 3860/4885ALDH1A1 3726/4885 |
| US-20190177308-A9 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | TRPM8, TRPM6, TRPM4 | TDP1 2442/4885HTT 4111/4885ALDH1A1 3880/4885 |
| US-20180273517-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | TRPM8, TRPM6, TRPM4 | TDP1 2442/4885HTT 4111/4885ALDH1A1 3880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.