Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 18/20 | 0.69 |
| ▸ | CTSL | P07711 | 18/20 | 0.69 |
| ▸ | CTSS | P25774 | 14/20 | 0.69 |
| ▸ | CTSB | P07858 | 7/20 | 0.69 |
| ▸ | CTSV | O60911 | 2/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14345781 | 1.00 | CTSK (0.69) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7488463 | 0.90 | CTSK (0.75) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4689766 | 0.89 | CTSK (0.62) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6836907 | 0.88 | CTSK (0.70) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6842082 | 0.88 | CTSK (0.70) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7451420 | 0.88 | CTSK (0.72) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6836936 | 0.88 | CTSK (0.69) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7112655 | 0.86 | CTSK (0.52) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6636938 | 0.85 | CTSK (0.50) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6636928 | 0.85 | CTSK (0.50) | CTSKCTSLCTSSCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235577-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2003-04-09 | — | — | EP | disclosed |
| EP-1235577-A2 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001034565-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-17 | — | — | WO | disclosed |