Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10959880 | 0.86 | RAB9A (0.57) | RAB9AMAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL30020898 | 0.85 | RAB9A (0.60) | RAB9AMAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL28609095 | 0.85 | RAB9A (0.60) | RAB9AMAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7496666 | 0.83 | RAB9A (0.66) | RAB9AMAPTSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL12661105 | 0.81 | RAB9A (0.55) | RAB9AMAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL18263482 | 0.80 | RAB9A (0.61) | RAB9AMAPTSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL10953577 | 0.80 | RAB9A (0.49) | RAB9AMAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9337119 | 0.80 | RAB9A (0.68) | RAB9AMAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL7530393 | 0.80 | RAB9A (0.60) | RAB9AMAPTSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL10959445 | 0.79 | RAB9A (0.63) | RAB9AMAPTSMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0978506-B1 | 2-PHENOXYANILINE DERIVATIVES | TAISHO PHARMACEUTICAL CO LTD (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-6156801-A | 2-phenoxyaniline derivatives | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2000-12-05 | — | — | US | disclosed |
| EP-0978506-A1 | 2-PHENOXYANILINE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2000-02-09 | — | — | EP | disclosed |