SCHEMBL7005443

SCHEMBL7005443

CC(CCCN1CCCC1=O)CN1CCCC1=O

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.61
ADRA1B P35368 4/20 0.43
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
PKM P14618 1/20 0.43
TSHR P16473 1/20 0.42
LMNA P02545 1/20 0.40
MALT1 Q9UDY8 1/20 0.40
ADRA1A P35348 2/20 0.40
ADRA1D P25100 1/20 0.40
RAB9A P51151 3/20 0.39
NPC1 O15118 2/20 0.39
BRD4 O60885 1/20 0.38
BRD2 P25440 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21217031 0.87 PIK3CD (0.61) PIK3CDTSHRLMNA
SCHEMBL1978043 0.87 PIK3CD (0.51) PIK3CDADRA1BKMT2AMEN1PKM
SCHEMBL5499961 0.85 PIK3CD (0.50) PIK3CDADRA1BKMT2AMEN1PKM
SCHEMBL104477 0.84 PIK3CD (0.61) PIK3CDADRA1BKMT2AMEN1PKM
SCHEMBL26855476 0.83 PIK3CD (0.65) PIK3CDKMT2AMEN1PKMTSHR
SCHEMBL21009232 0.83 PIK3CD (0.65) PIK3CDKMT2AMEN1PKMTSHR
SCHEMBL5501695 0.83 PIK3CD (0.47) PIK3CDADRA1BKMT2AMEN1PKM
SCHEMBL22021621 0.81 PIK3CD (0.53) PIK3CDADRA1BKMT2AMEN1PKM
SCHEMBL4336427 0.81 PIK3CD (0.49) PIK3CDADRA1BKMT2AMEN1PKM
SCHEMBL9018974 0.80 PIK3CD (0.51) PIK3CDADRA1BKMT2AMEN1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0755308-B1 ENGINE CLEANER COMPOSITION, METHOD, AND APPARATUS ENGINE FOG INC (US) 2003-02-26 EP claimed
EP-0755308-A4 ENGINE CLEANER COMPOSITION, METHOD, AND APPARATUS ENGINE FOG INC (US) 2000-04-12 EP claimed
US-5858942-A COMPOSITION COMPRISING SELECTED HETEROCYCLIC RING COMPOUND HAVING SPECIFIED BOILING POINT, BLEND OF WATER AND ACETONITRILE ADAMS LAWRENCE J (US) 1999-01-12 US claimed
EP-0755308-A1 ENGINE CLEANER COMPOSITION, METHOD, AND APPARATUS Engine Fog, Inc. (US) 1997-01-29 EP claimed
WO-1995028236-A1 ENGINE CLEANER COMPOSITION, METHOD, AND APPARATUS ENGINE FOG, INC. (US) 1995-10-26 WO claimed
EP-0755308-B1 ENGINE CLEANER COMPOSITION, METHOD, AND APPARATUS ENGINE FOG INC (US) 2003-02-26 EP disclosed
EP-0755308-A4 ENGINE CLEANER COMPOSITION, METHOD, AND APPARATUS ENGINE FOG INC (US) 2000-04-12 EP disclosed
US-5858942-A COMPOSITION COMPRISING SELECTED HETEROCYCLIC RING COMPOUND HAVING SPECIFIED BOILING POINT, BLEND OF WATER AND ACETONITRILE ADAMS LAWRENCE J (US) 1999-01-12 US disclosed
EP-0755308-A1 ENGINE CLEANER COMPOSITION, METHOD, AND APPARATUS Engine Fog, Inc. (US) 1997-01-29 EP disclosed
EP-0691954-A4 ASYMMETRICAL POLYPYRROLIDONYL COMPOUNDS HAVING A WIDE LIQUID RANGE ISP INVESTMENTS INC (US) 1996-04-24 EP disclosed
EP-0691954-A1 ASYMMETRICAL POLYPYRROLIDONYL COMPOUNDS HAVING A WIDE LIQUID RANGE ISP INVESTMENTS INC. (US) 1996-01-17 EP disclosed
WO-1995028236-A1 ENGINE CLEANER COMPOSITION, METHOD, AND APPARATUS ENGINE FOG, INC. (US) 1995-10-26 WO disclosed
WO-1994020462-A1 ASYMMETRICAL POLYPYRROLIDONYL COMPOUNDS HAVING A WIDE LIQUID RANGE ISP INVESTMENTS INC. (US) 1994-09-15 WO disclosed
US-5326880-A Asymmetrical polypyrrolidonyl compounds having a wide liquid range ISP INVESTMENTS INC. (US) 1994-07-05 US disclosed