Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1980364 | 0.98 | PIK3CD (0.47) | PIK3CDADRA1BKMT2AMEN1PKM | |
| SCHEMBL4329356 | 0.92 | PIK3CD (0.47) | PIK3CDADRA1BKMT2AMEN1PKM | |
| SCHEMBL5501695 | 0.89 | PIK3CD (0.47) | PIK3CDADRA1BKMT2AMEN1PKM | |
| SCHEMBL5499961 | 0.89 | PIK3CD (0.50) | PIK3CDADRA1BKMT2AMEN1PKM | |
| SCHEMBL22600522 | 0.89 | PIK3CD (0.53) | PIK3CDADRA1BKMT2AMEN1PKM | |
| SCHEMBL1978043 | 0.84 | PIK3CD (0.51) | PIK3CDADRA1BKMT2AMEN1PKM | |
| SCHEMBL19732459 | 0.84 | PIK3CD (0.47) | PIK3CDADRA1BKMT2AMEN1PKM | |
| SCHEMBL5502986 | 0.82 | PIK3CD (0.58) | PIK3CDADRA1BKMT2AMEN1PKM | |
| SCHEMBL4327116 | 0.82 | PIK3CD (0.58) | PIK3CDADRA1BKMT2AMEN1PKM | |
| SCHEMBL28358784 | 0.82 | PIK3CD (0.42) | PIK3CDKMT2AMEN1PKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105296244-A | Insulator electrified cleaning agent | YANG CHAO | 2016-02-03 | — | — | CN | claimed |
| CN-105296244-A | Insulator electrified cleaning agent | YANG CHAO | 2016-02-03 | — | — | CN | disclosed |
| US-7612216-B2 | Utilizing metal catalyst; one step; low cost | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-11-03 | — | — | US | disclosed |
| EP-1613573-A4 | PRODUCTION OF 5-METHYL-1-HYDROCARBYL-2-PYRROLIDONE BY REDUCTIVE AMINATION OF LEVULINIC ACID | DU PONT (US) | 2008-10-29 | — | — | EP | disclosed |
| EP-1605934-A4 | PRODUCTION OF 5-METHYL-N-(METHYL ARYL)-2-PYRROLIDONE, 5-METHYL-N-(METHYL CYCLOALKYL)-2-PYRROLIDONE AND 5-METHYL-N-ALKYL-2-PYRROLIDONE | DU PONT (US) | 2008-10-08 | — | — | EP | disclosed |
| EP-1605756-A4 | PRODUCTION OF 5-METHYL-N-ARYL-2-PYRROLIDONE AND 5-METHYL-N-ALKYL-2-PYRROLIDONE BY REDUCTIVE AMINATION OF LEVULINIC ACID ESTERS WITH ARYL AND ALKYL AMINES | DU PONT (US) | 2008-08-13 | — | — | EP | disclosed |
| EP-1606252-A4 | PRODUCTION OF N-(METHYL-ARYL)-2-LACTAM, N-(METHYL CYCLOAKLYL)-2-LACTAM AND N-ALKYL-2-LACTAM BY REDUCTIVE AMINATION OF LACTONES WITH ARYL AND ALKYCYANO COMPOUNDS | DU PONT (US) | 2008-08-06 | — | — | EP | disclosed |
| EP-1605933-A4 | PRODUCTION OF 5-METHYL-N-ARYL-2-PYRROLIDONE AND 5- METHYL-N-CYCLOALKYL-2-PYRROLIDONE BY REDUCTIVE AMINATION OF LEVULINIC ACID WITH ARYL AMINES | DU PONT (US) | 2008-07-02 | — | — | EP | disclosed |
| EP-1606046-A4 | PRODUCTION OF 5-METHYL-N-(METHYL ARYL)-2-PYRROLIDONE, 5-METHYL-N-(METHYL CYCLOALKYL)-2-PYRROLIDONE AND 5- METHYL-N-ALKYL-2-PYRROLIDONE BY REDUCTIVE AMINATION OF LEUVLINIC ACID ESTERS WITH CYANO COMPOUNDS | DU PONT (US) | 2008-06-25 | — | — | EP | disclosed |
| EP-1605753-A4 | PRODUCTION OF N-ARYL-2-LACTAM AND N-CYCLOALKYL-2-LACTAM BY REDUCTIVE AMINATION OF LACTONES WITH ARYL AMINES | DU PONT (US) | 2008-03-12 | — | — | EP | disclosed |
| WO-2004085347-A2 | PRODUCTION OF N-ARYL-2-LACTAM AND N-ALKYL-2-LACTAM BY REDUCTIVE AMINATION OF LACTONES WITH ARYL AND ALKYL NITRO COMPOUNDS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2004-10-07 | — | — | WO | disclosed |
| US-20040192936-A1 | PRODUCTION OF N-ARYL-2-LACTAM AND N-ALKYL-2-LACTAM BY REDUCTIVE AMINATION OF LACTONES WITH ARYL AND ALKYL NITRO COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-09-30 | — | — | US | disclosed |
| US-20040192932-A1 | Production of N-(methyl aryl)-2-lactam, N-(Methyl cycloalkyl)-2-lactam and N-alkyl-2-lactam by reductive amination of lactones with aryl and alkyl cyano compounds | E.I. DU PONT NEMOURS AND COMPANY | 2004-09-30 | — | — | US | disclosed |
| US-20040192939-A1 | Production of 5-methyl-N-aryl-2-pyrrolidone and 5-methyl-N-cycloalkyl-2-pyrrolidone by reductive amination of levulinic acid with aryl amines | MANZER LEO ERNEST (US) | 2004-09-30 | — | — | US | disclosed |
| US-20040192937-A1 | PRODUCTION OF N-ARYL-2-LACTAM AND N-CYCLOALKYL-2-LACTAM BY REDUCTIVE AMINATION OF LACTONES WITH ARYL AMINES | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-09-30 | — | — | US | disclosed |
| US-20040192935-A1 | Production of 5-methyl-N-(methyl aryl)-2-pyrrolidone, 5-methyl-N-(methyl cycloalkyl)-2-pyrrolidone and 5-methyl-N-alkyl-2-pyrrolidone by reductive amination of levulinic acid esters with cyano compounds | E.I. DU PONT DE NEMOURS AND COMPANY | 2004-09-30 | — | — | US | disclosed |
| US-20040192934-A1 | Production of 5-methyl-N-aryl-2-pyrrolidone and 5-methyl-N-alkyl-2-pyrrolidone by reductive amination of levulinic acid esters with nitro compounds | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-09-30 | — | — | US | disclosed |
| US-20040192938-A1 | Production of 5-mehyl-N-aryl-2-pyrrolidone and 5-methyl-N-alkyl-2-pyrrolidone by reductive of levulinic acid esters with aryl and alkyl amines | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-09-30 | — | — | US | disclosed |
| US-20040192933-A1 | Production of 5-methyl-1-hydrocarbyl-2-pyrrolidone by reductive amination of levulinic acid | E.I. DU PONT DE NEMOURS AND COMPANY | 2004-09-30 | — | — | US | disclosed |
| US-6743819-B1 | METAL CATALYST | E. I. DU PONTE DE NEMOURS AND COMPANY | 2004-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192934-A1 | Production of 5-methyl-N-aryl-2-pyrrolidone and 5-methyl-N-alkyl-2-pyrrolidone by reductive amination of levulinic acid esters with nitro compounds | PNPO, ALDH18A1, NLN | PIK3CD 4020/4885ADRA1B 4083/4885KMT2A 662/4885 |
| US-20040192933-A1 | Production of 5-methyl-1-hydrocarbyl-2-pyrrolidone by reductive amination of levulinic acid | ALDH18A1, PRMT5, PYCR1 | PIK3CD 3986/4885ADRA1B 4142/4885KMT2A 215/4885 |
| US-20040192939-A1 | Production of 5-methyl-N-aryl-2-pyrrolidone and 5-methyl-N-cycloalkyl-2-pyrrolidone by reductive amination of levulinic acid with aryl amines | PNPO, ASNS, PAH | PIK3CD 3531/4885ADRA1B 3426/4885KMT2A 328/4885 |
| US-20040192937-A1 | PRODUCTION OF N-ARYL-2-LACTAM AND N-CYCLOALKYL-2-LACTAM BY REDUCTIVE AMINATION OF LACTONES WITH ARYL AMINES | NIT2, AAAS, ASNS | PIK3CD 3013/4885ADRA1B 2120/4885KMT2A 152/4885 |
| US-20040192936-A1 | PRODUCTION OF N-ARYL-2-LACTAM AND N-ALKYL-2-LACTAM BY REDUCTIVE AMINATION OF LACTONES WITH ARYL AND ALKYL NITRO COMPOUNDS | NIT2, NANS, ASNS | PIK3CD 3189/4885ADRA1B 3457/4885KMT2A 349/4885 |
| US-20040192938-A1 | Production of 5-mehyl-N-aryl-2-pyrrolidone and 5-methyl-N-alkyl-2-pyrrolidone by reductive of levulinic acid esters with aryl and alkyl amines | PAH, ALDH18A1, PNPO | PIK3CD 4267/4885ADRA1B 3895/4885KMT2A 285/4885 |
| US-20040192932-A1 | Production of N-(methyl aryl)-2-lactam, N-(Methyl cycloalkyl)-2-lactam and N-alkyl-2-lactam by reductive amination of lactones with aryl and alkyl cyano compounds | AAAS, ASNS, NIT2 | PIK3CD 2208/4885ADRA1B 3946/4885KMT2A 91/4885 |
| US-20040192935-A1 | Production of 5-methyl-N-(methyl aryl)-2-pyrrolidone, 5-methyl-N-(methyl cycloalkyl)-2-pyrrolidone and 5-methyl-N-alkyl-2-pyrrolidone by reductive amination of levulinic acid esters with cyano compounds | PNPO, ALDH18A1, RIMKLA | PIK3CD 3239/4885ADRA1B 4146/4885KMT2A 656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.