Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 2/20 | 0.39 |
| ▸ | CHAT | P28329 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6553126 | 0.80 | ALDH1A1 (0.43) | MAOBCYP1A2ALDH1A1CYP2D6 | |
| SCHEMBL7008999 | 0.79 | IDO1 (0.47) | MAOBCYP1A2IDO1TDO2MAPT | |
| SCHEMBL18243444 | 0.72 | CHRM5 (0.52) | CHRM5MAOBCYP1A2CYP2C9FBP1 | |
| SCHEMBL7521832 | 0.72 | ACP3 (0.50) | ACP3IDO1TDO2KMT2AALDH1A1 | |
| Benzaldehyde SCHEMBL20557183 | 0.72 | ALDH1A1 (0.61) | CHRM5MAOBCYP1A2CYP2C9FBP1 | |
| SCHEMBL23457219 | 0.72 | CHRM5 (0.52) | CHRM5MAOBCYP1A2CYP2C9FBP1 | |
| SCHEMBL3301775 | 0.71 | CHRM5 (0.56) | CHRM5MAOBCYP1A2CYP2C9FBP1 | |
| SCHEMBL699875 | 0.71 | CHAT (0.66) | CHRM5MAOBCYP1A2CYP2C9FBP1 | |
| SCHEMBL29446280 | 0.71 | CHAT (0.66) | CHRM5MAOBCYP1A2CYP2C9FBP1 | |
| SCHEMBL699874 | 0.71 | CHAT (0.66) | CHRM5MAOBCYP1A2CYP2C9FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1267906-A1 | LACTAMS AS INHIBITORS OF A-BETA PROTEIN PRODUCTION | Bristol-Myers Squibb Pharma Company (US) | 2003-01-02 | — | — | EP | claimed |
| WO-2001072324-A1 | LACTAMS AS INHIBITORS OF A-BETA PROTEIN PRODUCTION | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2001-10-04 | — | — | WO | claimed |