Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 19/20 | 0.66 |
| ▸ | CCR7 | P32248 | 8/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7008307 | 0.86 | CXCR2 (0.63) | CXCR2CCR7TP53 | |
| SCHEMBL23510063 | 0.81 | MEN1 (0.53) | CXCR2TP53 | |
| SCHEMBL7005047 | 0.80 | CXCR2 (1.00) | CXCR2CCR7 | |
| SCHEMBL490245 | 0.74 | CXCR2 (0.50) | CXCR2CCR7 | |
| SCHEMBL6353452 | 0.72 | CXCR2 (0.44) | CXCR2CCR7 | |
| SCHEMBL14214462 | 0.70 | CXCR2 (0.47) | CXCR2CCR7 | |
| SCHEMBL14214579 | 0.70 | CXCR2 (0.47) | CXCR2CCR7 | |
| SCHEMBL3605166 | 0.69 | CXCR2 (0.59) | CXCR2 | |
| SCHEMBL4084677 | 0.69 | CXCR2 (0.70) | CXCR2CCR7 | |
| SCHEMBL2899683 | 0.69 | NPC1 (0.48) | CXCR2CCR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1257555-B1 | PYRIMIDINE COMPOUNDS AND THEIR USE AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | ASTRAZENECA AB (SE) | 2003-12-03 | — | — | EP | disclosed |