Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7596612 | 0.83 | CXCR2 (0.70) | CXCR2CCR7 | |
| SCHEMBL4084677 | 0.81 | CXCR2 (0.70) | CXCR2CCR7 | |
| SCHEMBL7005657 | 0.80 | CXCR2 (0.66) | CXCR2CCR7 | |
| SCHEMBL5256624 | 0.80 | CXCR2 (0.70) | CXCR2CCR7 | |
| SCHEMBL5191224 | 0.80 | CXCR2 (0.69) | CXCR2CCR7 | |
| SCHEMBL6360635 | 0.80 | CXCR2 (0.75) | CXCR2CCR7 | |
| SCHEMBL3849356 | 0.79 | CXCR2 (1.00) | CXCR2CCR7 | |
| SCHEMBL3849366 | 0.79 | CXCR2 (1.00) | CXCR2CCR7 | |
| SCHEMBL5951464 | 0.79 | CXCR2 (0.80) | CXCR2CCR7 | |
| SCHEMBL3850612 | 0.79 | CXCR2 (1.00) | CXCR2CCR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1257555-B1 | PYRIMIDINE COMPOUNDS AND THEIR USE AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | ASTRAZENECA AB (SE) | 2003-12-03 | — | — | EP | claimed |
| EP-1257555-B1 | PYRIMIDINE COMPOUNDS AND THEIR USE AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | ASTRAZENECA AB (SE) | 2003-12-03 | — | — | EP | disclosed |
| EP-1257555-A1 | PYRIMIDINE COMPOUNDS AND THEIR USE AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | AstraZeneca AB (SE) | 2002-11-20 | — | — | EP | disclosed |
| WO-2001058906-A1 | PYRIMIDINE COMPOUNDS AND THEIR USE AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | ASTRAZENECA AB (SE) | 2001-08-16 | — | — | WO | disclosed |