Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7005673 | 1.00 | CYP19A1 (0.33) | CYP19A1 | |
| SCHEMBL5497620 | 0.87 | CYP19A1 (0.34) | CYP19A1 | |
| SCHEMBL5497614 | 0.87 | CYP19A1 (0.34) | CYP19A1 | |
| SCHEMBL9198803 | 0.76 | CYP19A1 (0.38) | CYP19A1 | |
| SCHEMBL5492401 | 0.76 | CYP19A1 (0.34) | CYP19A1 | |
| SCHEMBL13863146 | 0.74 | CYP19A1 (0.33) | CYP19A1 | |
| SCHEMBL17930991 | 0.73 | PARP1 (0.35) | — | |
| SCHEMBL9194590 | 0.71 | CYP19A1 (0.40) | CYP19A1 | |
| SCHEMBL2842945 | 0.71 | ALDH1A1 (0.36) | — | |
| SCHEMBL2842338 | 0.71 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1193270-B1 | Pyrrolobenzodiazepines | SPIROGEN LTD (GB) | 2003-05-14 | — | — | EP | disclosed |