Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 17/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5231311 | 0.99 | DPP4 (0.43) | DPP4ALDH1A1LMNAMAPTHPGD | |
| Hydrochloric Acid SCHEMBL5235033 | 0.91 | DPP4 (0.44) | DPP4MAPTMAPK1AAK1 | |
| Hydrochloric Acid SCHEMBL5234616 | 0.89 | DPP4 (0.43) | DPP4ALDH1A1MAPTHPGDMAPK1 | |
| Hydrochloric Acid SCHEMBL5239297 | 0.89 | DPP4 (0.43) | DPP4ALDH1A1MAPTHPGDMAPK1 | |
| Hydrochloric Acid SCHEMBL5237649 | 0.88 | DPP4 (0.42) | DPP4 | |
| SCHEMBL7005880 | 0.87 | DPP4 (0.41) | DPP4ALDH1A1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL5234677 | 0.87 | DPP4 (0.46) | DPP4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5238860 | 0.86 | DPP4 (0.42) | DPP4ALDH1A1MAPTMAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL5239225 | 0.86 | DPP4 (0.41) | DPP4ALDH1A1MAPTMAPK1 | |
| SCHEMBL5238915 | 0.85 | DPP4 (0.52) | DPP4ALDH1A1LMNAHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355886-B1 | FUSED HETEROCYCLIC COMPOUNDS | TAKEDA PHARMACEUTICAL (JP) | 2007-07-11 | — | — | EP | disclosed |