SCHEMBL7005923

SCHEMBL7005923

CCC(CCCCCCCCCCCCCC(=O)O)(c1ccccc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC11 Q96DB2 7/20 0.47
HDAC3 O15379 2/20 0.47
HDAC4 P56524 2/20 0.47
HDAC1 Q13547 2/20 0.47
HDAC7 Q8WUI4 2/20 0.47
HDAC2 Q92769 2/20 0.47
HDAC10 Q969S8 2/20 0.47
HDAC8 Q9BY41 2/20 0.47
HDAC6 Q9UBN7 2/20 0.47
HDAC9 Q9UKV0 2/20 0.47
HDAC5 Q9UQL6 2/20 0.47
MAPT P10636 1/20 0.47
RXFP1 Q9HBX9 1/20 0.47
NPSR1 Q6W5P4 1/20 0.42
GPR84 Q9NQS5 7/20 0.42
PPARG P37231 7/20 0.42
PPARD Q03181 7/20 0.42
PPARA Q07869 7/20 0.42
TSHR P16473 4/20 0.42
PTPN1 P18031 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5705332 1.00 HDAC11 (0.47) HDAC11HDAC3HDAC4HDAC1HDAC7
SCHEMBL7025067 1.00 HDAC11 (0.47) HDAC11HDAC3HDAC4HDAC1HDAC7
SCHEMBL14360769 0.86 HDAC3 (0.50) HDAC11HDAC3HDAC4HDAC1HDAC7
SCHEMBL7569647 0.86 HDAC3 (0.50) HDAC11HDAC3HDAC4HDAC1HDAC7
SCHEMBL14360027 0.86 HDAC3 (0.48) HDAC11HDAC3HDAC4HDAC1HDAC7
SCHEMBL7008505 0.86 KMT2A (0.47) MAPTMEN1ESR1KMT2A
SCHEMBL5705319 0.86 KMT2A (0.47) MAPTMEN1ESR1KMT2A
SCHEMBL6232916 0.86 SIGMAR1 (0.42) ESR1MAPK1
SCHEMBL14360509 0.85 HDAC3 (0.49) HDAC11HDAC3HDAC4HDAC1HDAC7
SCHEMBL7006017 0.85 HDAC3 (0.49) HDAC11HDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1326822-A2 KETONE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES Esperion Therapeutics Inc. (US) 2003-07-16 EP claimed
WO-2002030860-A2 KETONE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES ESPERION THERAPEUTICS, INC. (US) 2002-04-18 WO claimed
EP-1326822-A2 KETONE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES Esperion Therapeutics Inc. (US) 2003-07-16 EP disclosed
WO-2002030860-A2 KETONE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES ESPERION THERAPEUTICS, INC. (US) 2002-04-18 WO disclosed