Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | EDNRB | P24530 | 2/20 | 0.41 |
| ▸ | EDNRA | P25101 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.41 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7013058 | 0.85 | LMNA (0.50) | KMT2AMAPTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL6628690 | 0.80 | KMT2A (0.51) | KMT2AMAPTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL7011867 | 0.78 | KMT2A (0.50) | KMT2AMAPTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL9668616 | 0.77 | KMT2A (0.44) | KMT2AMAPTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL9241106 | 0.77 | — | — | |
| SCHEMBL9191924 | 0.77 | LMNA (0.50) | KMT2AMAPTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL28589911 | 0.75 | KMT2A (0.47) | KMT2AMAPTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL9852833 | 0.74 | PDE10A (0.33) | KMT2AKDM4E | |
| SCHEMBL7012356 | 0.74 | LMNA (0.56) | ALDH1A1SMN1; SMN2KDM4ELMNAEDNRB | |
| SCHEMBL2844487 | 0.72 | KDM4E (0.50) | KMT2AALDH1A1KDM4ELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353640-B2 | Heterocyclic N-acylsulphonamides, process for their preparation, agents containing them and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE GMBH (DE) | 2003-10-15 | — | — | EP | disclosed |
| EP-0353640-B1 | Heterocyclic N-acylsulphonamides, process for their preparation, agents containing them and their use as herbicides and plant growth regulators | HOECHST SCHERING AGREVO GMBH (DE) | 1995-04-12 | — | — | EP | disclosed |
| EP-0353640-A2 | Heterocyclic N-acylsulphonamides, process for their preparation, agents containing them and their use as herbicides and plant growth regulators | Hoechst Schering AgrEvo GmbH (DE) | 1990-02-07 | — | — | EP | disclosed |