Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 5/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 3/20 | 0.41 |
| ▸ | TLR1 | Q15399 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7006409 | 1.00 | SMN1; SMN2 (0.51) | SMN1; SMN2NPSR1KDM1AEPHX2CNR1 | |
| SCHEMBL14882154 | 0.84 | EPHX2 (0.47) | SMN1; SMN2NPSR1KDM1AEPHX2MAOB | |
| SCHEMBL14882153 | 0.84 | EPHX2 (0.47) | SMN1; SMN2NPSR1KDM1AEPHX2MAOB | |
| SCHEMBL3028226 | 0.83 | SMN1; SMN2 (0.57) | SMN1; SMN2NPSR1KDM1AEPHX2CNR1 | |
| SCHEMBL6154005 | 0.81 | SMN1; SMN2 (0.73) | SMN1; SMN2NPSR1KDM1AEPHX2CNR1 | |
| SCHEMBL7980208 | 0.81 | SMN1; SMN2 (0.73) | SMN1; SMN2NPSR1KDM1AEPHX2CNR1 | |
| SCHEMBL3457343 | 0.81 | SMN1; SMN2 (0.73) | SMN1; SMN2NPSR1KDM1AEPHX2CNR1 | |
| SCHEMBL6153775 | 0.81 | SMN1; SMN2 (0.73) | SMN1; SMN2NPSR1KDM1AEPHX2CNR1 | |
| SCHEMBL3048130 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2NPSR1KDM1AEPHX2CNR1 | |
| SCHEMBL20187076 | 0.81 | KDM1A (0.51) | SMN1; SMN2NPSR1KDM1AEPHX2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996621-B1 | TRIAZOLO[4,5-d]PYRIMIDINE DERIVATIVES AS ANTI-THROMBOTIC AGENTS | ASTRAZENECA AB (SE) | 2003-10-01 | — | — | EP | disclosed |